치주수술 및 인공치아매식술 후 Myprodol의 동통 억제 효과에 대한 연구

Abstract

"Although various analgesics have been administrated for postoperative pain control, postoperative pain has not been adequately controlled . The purpose of this study was to evaluate the effects and patient's satisfaction of Myprodol􄠶(combination analgesics with codeine, ibuprofen, paracetamol) compared to Acetamionphen and placebo drug after periodontal surgery and dental implant surgery. We studied 98 cases of outpatients which were composed of 67 cases of flap operation(which separated to 3 groups: Placebo group(n=25), Myprodol􄠶 group(n=22), Acetaminophen group(n=20)) and 21 cases of dental implant surgery(which separated to 3 groups : Placebo group(n=10), Myprodol􄠶 group(n=12), Acetaminophen group(n=9)). We evaluated the postoperative pain(Pain 1), Pain after first drug administraion(Pain 2), the degrees of pain reduction(pain 3), patient's satisfaction for drug, and side-effects. We obtained following results; 1. In Pain 1, making a comparison among groups, there was no significant difference in both cases of flap operation-group and dental implant surgery-group 2. In Pain 2, establishing a comparison among groups, there was no significant difference in flap operationgroup, but significant difference was seen between placebo group and Myprodol􄠶 group in cases of dental implant surgery group(P<0.05). 3. In Pain 3, making a comparison among groups, Myprodol􄠶 group showed significant differences compared to placebo group and Acetaminophen group in both cases of flap peration group and dental implant surgery group(P<0.05). 4. In patient's satisfactory score, making a comparison among groups, there were significant differences between placebo group and Myprodol􄠶 group in cases of flap operation group and between Myprodol􄠶 group and Acetaminophen group in cases of dental implant surgery group(P<0.05). 5. Making a comparison in side-dffect, no significant differrence was seen. Our conclusion is that Myprodol􄠶 is a effective oral analgesics to the patients who underwent periodontal surgery or implant surgery for it's synergism among three dugs."