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MUC5AC의 눈물층에서의 존재 양상
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김응권 | - |
dc.date.accessioned | 2019-11-11T05:53:26Z | - |
dc.date.available | 2019-11-11T05:53:26Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0378-6471 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/172242 | - |
dc.description.abstract | The mucous layer located on the cornea epithelial surface is mainly composed of mucin.It is unique in being composed of a central protein back bone surrounded by an outermost dense oligosaccharide matrix, yet its pre-cise composition is still unknown. Conjunctival goblet cells have been known to express the mucin MUC5AC. We attempted to reveal the presence of the secretory mucin MUC5AC as a component of the mucous layer in the rabbit corneal tear film. An antibody to a MUC5AC peptide was used to detect the MUC5AC mucin present in the tear film by immunohistochemistry. Human conjuncti-val impression cytology and immunohistochemistry were done with the same antibody. The MUC5AC mucin was observed in the precorneal tear film and con-junctival goblet cells by immunohistochemistry.The MUC5AC mucin is a component of the mucous layer and is produced by the goblet cells of con-junctiva. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean | - |
dc.publisher | 대한안과학회 | - |
dc.relation.isPartOf | Journal of the Korean Ophthalmological Society (대한안과학회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | MUC5AC의 눈물층에서의 존재 양상 | - |
dc.title.alternative | The characteristics of MUC5AC in the corneal tear film | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학교실) | - |
dc.contributor.googleauthor | 정승은 | - |
dc.contributor.googleauthor | 김소영 | - |
dc.contributor.googleauthor | 서경률 | - |
dc.contributor.googleauthor | 박중원 | - |
dc.contributor.googleauthor | 정수연 | - |
dc.contributor.googleauthor | 성제경 | - |
dc.contributor.googleauthor | 김응권 | - |
dc.contributor.localId | A00831 | - |
dc.relation.journalcode | J01838 | - |
dc.identifier.eissn | 2092-9374 | - |
dc.subject.keyword | Cornea | - |
dc.subject.keyword | Tear film | - |
dc.subject.keyword | Mucin | - |
dc.subject.keyword | MUC5AC | - |
dc.contributor.alternativeName | Kim, Eung Kweon | - |
dc.contributor.affiliatedAuthor | 김응권 | - |
dc.citation.volume | 41 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 1304 | - |
dc.citation.endPage | 1309 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Ophthalmological Society (대한안과학회지), Vol.41(6) : 1304-1309, 2000 | - |
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