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다카야수 동맥염과 동반된 초점성 분절성 사구체경화증 1예

Other Titles
 A Case of Focal Segmental Glomeruloscierosis in Takayasu´s Arteritis 
 강신명  ;  송영수  ;  김주성  ;  윤수영  ;  이루다  ;  최규헌  ;  조승연  ;  이호영  ;  한대석  ;  정현주 
 Korean Journal of Nephrology (대한신장학회지), Vol.19(5) : 959-964, 2000 
Journal Title
Korean Journal of Nephrology(대한신장학회지)
Issue Date
Takayasu´s arteritis ; Focal segmental glomeruloscleposis ; Focal segmental glomerulosclerosis
Takayasu's arteritis(TA) is a chronic inflammatory and obliterative disease of medium- and large-sized arteries characterized by a strong predilection for the aortic arch and its branches. Renal involvement is usually manifested by renovascular hypertension. Glomerular involvement is rare and largely exists as a mild mesangial proliferative glomerulonephritis, commonly manifesting microscopic hematuria and proteinuria. The association of glomerular disease with TA is of interest since common immunologic mechanisms are proposed for the pathogenesis of both entities. We report a case of TA associated with focal segmental glomerulosclerosis. The patient presented with hypertension(Upper limb; Rt. 200/80mmHg, Lt. 95/60mmHg, Lower limb; Rt. 140/90mmHg, Lt. 110/70mmHg) and nephrotic syndrome(Serum albumin: 2.3g/dL, cholesterol: 454mg/dL, BUN: 18.0mg/dL, creatinine 1.3mg/dL, 24-hour urine protein: 5.17g). Digital substraction angiography showed multiple narrowing and occlusive changes of aortic arch and its branches. Renal biopsy was interpreted as focal segmental glomerulosclerosis. Therapy was instituted with prednisolone.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Choi, Kyu Hun(최규헌) ORCID logo https://orcid.org/0000-0003-0095-9011
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