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케톤식이요법으로 6개월 이상 완전히 발작이 조절된 난치성 소아간질의 임상특징 및 뇌파특성

Other Titles
 Clinical and Electrographic Characteristics of Intractable Childhood Epilepsy with Complete Seizure Remission Over 6 Months After Ketogenic Diet 
Authors
 김영래  ;  김흥동 
Citation
 Journal of the Korean Child Neurology Society (대한소아신경학회지), Vol.8(2) : 242-249, 2000 
Journal Title
 Journal of the Korean Child Neurology Society (대한소아신경학회지) 
ISSN
 1226-6884 
Issue Date
2000
Keywords
Ketogenic diet ; Intractable childhood epilepsy
Abstract
Purpose: The efficacy of ketogenic diet in intractable childhood epilepsy has been reported in Korea. The aim of this retrospective study is to elicit the clinical and electrophysiological characteristics of intractable childhood epilepsy, who can be successfully treated by ketogenic diet and to determine the favorable outcome group for ketogenic diet in intractable chilhood epilepsy. Methods: We investigated clinical seizure type, epilepsy classification, underlying etiologies, clinical characteristics, EEG findings, response to treatments, and prognosis were studied in 41 patients with complete seizure remission over 6 months after ketogenic diet as compared with unsuccessful group among 96 patients of trial from July 1995 to October 1999 at the pediatric department of and epilepsy center at Sang-gye Paik Hospital, Inje University. Results: 1) Complete seizure remission over 6 months were obtained in 15 patients of infantile spasms(IS), 6 cases of Lennox-Gastaut syndrorne(LGS), 4 cases of periodic spasms, 3 cases of severe myoclonic epilepsy in infancy(SMEI), 1 case of Landau-Kleffner syndrome, 8 cases of other type of partial epilepsies. 2) Ketogenic diet was more effective in infantile spasms and periodic spasms but least effective in Lennox-Gastaut syndome. 3) In same types of epilepsies, ketogenic diet was more effective in patients with less frequent seizures, less severe EEG findings and earlier controlling seizures. Conclusions: Ketogenic diet was most effective in infantile spasms, patients with less frequent seizure in same type of epilepsy, less severe EEG findings in same seizure type, and patients who seizures stopped sooner after administration of ketogenic diet.
Full Text
http://digital.kyobobook.co.kr/digital/article/articleDetail.ink?selectedLargeCategory=006&barcode=4010022738326
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Heung Dong(김흥동) ORCID logo https://orcid.org/0000-0002-8031-7336
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/172162
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