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정상임신과 자궁외 임신 사이의 융모막 융모 telomerase 활성도의 비교

Other Titles
 Comparision of telomerase activity in human chorionic villi between eutopic and ectopic pregnancies 
 김세광  ;  정영내  ;  정현철  ;  박규현  ;  김창한  ;  박지현  ;  김성훈  ;  김정연  ;  배상욱  ;  박기현  ;  조동제  ;  송찬호 
 Korean Journal of Obstetrics and Gynecology (대한산부인과학회잡지), Vol.43(8) : 1431-1436, 2000 
Journal Title
Korean Journal of Obstetrics and Gynecology(대한산부인과학회잡지)
Issue Date
telomerase ; telomerase ; Telomerase activity ; Chorionic villi ; Ectopic pregnancy
Objectives : To compare the presence of telomerase activity(TA) in the chorionic villi between eutopic and ectopic first trimester human pregnancies. Methods : Human chorionic villi were obtained from eleven normal eutopic pregnant women who underwent an elective abortion, and from eleven women with ectopic pregnancy who underwent a salpingectomy for tubal pregnancy. TA was analyzed by radioisotope polymerase chain reaction based telomeric repeat amplification protocol(TRAP) assay. Results : TA was expressed in 5 of 11 (45.5%) in eutopic pregnancies, and in 7 of 11(63.6%) in ectopic pregnancies. Chorionic villi in ectopic pregnancies were expressed more frequently than those of eutopic pregnancies, this difference was not significant.(p>0.05) Conclusion : Our results suggest that the expression of TA in human chorionic villi was not affected according to the implantation site during early placental development.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sei Kwang(김세광)
Bai, Sang Wook(배상욱) ORCID logo https://orcid.org/0000-0001-7724-7552
Chung, Hyun Cheol(정현철) ORCID logo https://orcid.org/0000-0002-0920-9471
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