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Lidocaine과 Bupivacaine의 다양한 혼합비에 따른 신경전도 차단 양상의 변화에 대한 연구

Other Titles
 Patterns of nerve conduction blockade by differential combinations of lidocaine-bupivacain mixture 
Authors
 조성강  ;  임중우  ;  임상수  ;  한성민  ;  공현석  ;  최윤 
Citation
 Journal of Korean Society of Anesthesiologist (대한마취과학회지), Vol.38(4) : 708-712, 2000 
Journal Title
Journal of Korean Society of Anesthesiologist(대한마취과학회지)
ISSN
 0302-5780 
Issue Date
2000
Keywords
Anesthetics ; local ; bupivacaine ; mixture ; onset ; recovery ; Animals ; rats ; Nerve ; Sciatic
Abstract
The effects of intermittent administration of parathyroid hormone on fracture healing in ovariectomized rats were examined to evaluate its potential use as a therapeutic agent for osteoporotic fractures. Three months postovariectomy, bilateral tibial shaft fractures were induced and stabilized by intramedullary nailing with Kirschner wires. Saline, 17beta-estradiol (Sigma Chemical Corp, St Louis, Mo), or recombinant human parathyroid hormone (1-84) (Korean Green-Cross Pharm Corp, Seoul, Korea) was given once a day for 30 consecutive days during fracture healing. Fracture healing was assessed by morphometric and mechanical analysis of fracture callus. Intermittent parathyroid hormone administration increased the morphometric and mechanical parameters in a dose-dependent manner. A bone-resorption inhibiting agent, 17beta-estradiol did not offer advantage in terms of fracture healing in ovariectomized rats. Findings suggest intermittent parathyroid hormone administration may benefit osteoporosis and fracture.
Files in This Item:
T200001629.pdf Download
DOI
10.4097/kjae.2000.38.4.708
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Physiology (생리학교실) > 1. Journal Papers
Yonsei Authors
Leem, Joong Woo(임중우) ORCID logo https://orcid.org/0000-0002-1605-2230
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/172059
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