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원발성 피부 림프종의 치료 성적과 생존율

Other Titles
 Treatment outcome and survival rate of primary cutaneous lymphomas 
Authors
 김진석  ;  한지숙  ;  강태수  ;  장준호  ;  민유홍  ;  고윤웅  ;  서창옥  ;  이민걸 
Citation
 Korean Journal of Medicine (대한내과학회지), Vol.59(1) : 47-58, 2000 
Journal Title
Korean Journal of Medicine(대한내과학회지)
ISSN
 1226-329X 
Issue Date
2000
Keywords
Skin neoplasm ; Lymphoma: Survival rate
Abstract
Background : Primary cutaneous lymphomas are very rare type of malignant lymphomas . They represent a heterogeneous group of T - cell and B- cell lymphomas with cons iderable variations in clinical presentation, histopathology, immunophenotype, and prognos is . In this report, we evaluated the clinical characteristics of primary cutaneous lymphoma according to their clinical stages and histopathologic types .
Methods : From January, 1985 to Jun, 1999, 23 patients with histopathologic diagnosis of primary cutaneous lymphoma were evaluated retrospectively.
Results : The mean age was 48.5 years at the time of diagnos is of primary cutaneous lymphomas, and the most frequent form of cutaneous involvement was nodule(35%). T he average duration from the occurrence of cutaneous lesion to the diagnosis of primary cutaneous lymphoma was 29.8 months. There were 20 cases(87%) of primary cutaneous T cell lymphomas, whereas primary cutaneous B cell lymphomas were seen in 3 cases (13%). The patients with stage I were 9 cases (39%), whereas the patients with s tage IV were 10 cases(43%). Complete remiss ion rate was 29% and partial remiss ion rate was 57%. Median disease- free survival duration was 7 months and median overall survival duration was 33 months . One- year overall survival rate was 63.3% and 3- year overall survival rate was 56.3%.
Conclusion : Primary cutaneous lymphomas were usually diagnosed at a far- advanced stage, and showed poor treatment results. Therefore early diagnosis is important to improve the survival rate. There should be carefully follow- up and repeated tis sue diagnos is of the s kin les ions which had a suspicion of primary cutaneous lymphoma and had not responded to conservative treatment.(Korean J Med 59:47- 58, 2000)
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Min Geol(이민걸) ORCID logo https://orcid.org/0000-0001-7040-5335
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/172029
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