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A case of membranoproliferative glomerulonephritis associated with a hydatidiform mole.

Authors
 Byoung Geun Han  ;  Mi Hye Kim  ;  Eung Ho Karl  ;  Sun Won Hong  ;  Seung Ok Choi 
Citation
 Yonsei Medical Journal, Vol.41(3) : 407-410, 2000 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2000
MeSH
Case Report ; Diagnosis, Differential ; Edema/etiology ; Female ; Glomerulonephritis, Membranoproliferative/etiology* ; Glomerulonephritis, ; Membranoproliferative/pathology ; Hematuria/etiology ; Human ; Hydatidiform Mole/complications* ; Hydatidiform Mole/diagnosis* ; Hydatidiform Mole/therapy ; Middle Age ; Pregnancy ; Proteinuria/etiology ; Uterine Neoplasms/complications* ; Uterine Neoplasms/diagnosis* ; Uterine Neoplasms/therapy
Keywords
Glomerulonephritis ; hydatidiform mole
Abstract
We treated a 54-year-old woman who was suffering from membranoproliferative glomerulonephritis associated with a complete type of hydatidiform mole. The renal manifestations were proteinuria and hematuria. A renal biopsy, performed before gynecologic management, disclosed focal and segmental subendothelial deposits with a proliferation of the mesangial cell and showed irregularly thickened capillary loops by light and electronmicroscoy. Genralized edema, proteinuria and hematuria were completely recovered by suction and curettage of the hydatidiform mole with prophylactic chemotherapy. The clinical manifestation of earlier presented 3 cases have been the nephrotic syndrome. The common feature of them was a complete remission of the nephropathy after the removal of the hydatidiform mole. The relationship between the hydatidiform mole and glomerulonephritis remains unresolved at present. But we concluded that the hydatidiform mole might be a cause of glomerulonephritis in this case.
Files in This Item:
T200003277.pdf Download
DOI
10.3349/ymj.2000.41.3.407
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
Yonsei Authors
Hong, Soon Won(홍순원) ORCID logo https://orcid.org/0000-0002-0324-2414
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/171924
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