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Serological observation of Toxoplasma gondii prevalence in Apodemus agrarius, a dominant species of field rodents in Korea.

Authors
 Soung-Hoo Jeon  ;  Tai-Soon Yong 
Citation
 Yonsei Medical Journal, Vol.41(4) : 491-496, 2000 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2000
MeSH
Animals ; Antibodies, Protozoan/blood* ; Antigens, Protozoan/immunology ; Enzyme-Linked Immunosorbent Assay ; Immunoblotting ; Molecular Weight ; Muridae/parasitology* ; Seroepidemiologic Studies ; Toxoplasma/immunology ; Toxoplasma/isolation & purification*
Keywords
Toxoplasma Gondii ; Apodemus Agrarius ; Prevalence ; Antibody
Abstract
Field rodents involved in ecological food chains and which are the prey of carnivores in the natural environment may serve as reservoir hosts for Toxoplasma gondii infection in humans, however, no data has been published to date in Korea. A total of 1,008 Apodemus agrarius, a dominant species of field rodents in Korea, were trapped at various locations around the country, and their serum antibody (IgG) levels to T. gondii were examined by ELISA. The mean absorbance was 0.11, and fifteen samples (1.49%) showed positive titers from 0.18 to 0.59. The seropositive samples were analyzed by immunoblot. Five of them showed reactive bands to T. gondii water soluble antigens of 30, 35, and 43 kDa. This immunoblot analysis showed very similar patterns to that obtained using sera of experimentally infected mice with T. gondii. The present study presents indirect evidence of the existence of T. gondii in field rodents in Korea.
Files in This Item:
T200002465.pdf Download
DOI
10.3349/ymj.2000.41.4.491
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Tropica Medicine (열대의학교실) > 1. Journal Papers
Yonsei Authors
Yong, Tai Soon(용태순) ORCID logo https://orcid.org/0000-0002-3445-0769
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/171906
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