242 344

Cited 70 times in

Tissue-engineered human living skin substitutes : development and clinical application.

Authors
 Kwang Hoon Lee 
Citation
 Yonsei Medical Journal, Vol.41(6) : 774-779, 2000 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2000
MeSH
Biocompatible Materials ; Biomedical Engineering* ; Chondroitin Sulfates ; Collagen ; Humans ; Keratinocytes/transplantation ; Skin, Artificial*
Keywords
Tissue engineering ; skin ; skin substitutes
Abstract
The skin acts as a barrier to exogenous substances, pathogens, and trauma. Skin defects caused by burns, venous ulcer, diabetic ulcer, or acute injury occasionally induce life-threatening situations. Tissue engineering provides an alternative for autologous or allogeneic tissue transplantation, which is required because of donor site limitations and the risks of transmitting infection. Currently, skin substitutes are made of only extracellular matrix, mainly cells, or combination of cells and matrices. New biotechnological approaches have led to the development of the skin equivalent, the closest match yet to native human skin in terms of histological and functional properties. This review article focuses upon the development of the in vitro and in vivo epidermis and dermis and their clinical applications.
Files in This Item:
T200002304.pdf Download
DOI
10.3349/ymj.2000.41.6.774
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Kwang Hoon(이광훈)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/171904
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links