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The use of high-resolution computed tomography in the evaluation of pulmonary hemodynamics in patients with congenital heart disease: in pulmonary vessels larger than 1 mm in diameter.

 K.O. Choe  ;  Y.K. Hong  ;  H.J. Kim  ;  S.H. Joo  ;  B.K. Cho  ;  B.C. Chang  ;  S.Y. Cho  ;  W.H. Shim  ;  N.S. Chung 
 Pediatric Cardiology, Vol.21(3) : 202-210, 2000 
Journal Title
Issue Date
Adolescent ; Adult ; Blood Pressure ; Double Outlet Right Ventricle/diagnostic imaging ; Double Outlet Right Ventricle/physiopathology* ; Female ; Heart Septal Defects, Atrial/diagnostic imaging ; Heart Septal Defects, Atrial/physiopathology* ; Heart Septal Defects, Ventricular/diagnostic imaging ; Heart Septal Defects, Ventricular/physiopathology* ; Humans ; Male ; Middle Aged ; Pulmonary Artery/physiopathology* ; Pulmonary Veins/physiopathology* ; Tomography, X-Ray Computed/methods* ; Vascular Resistance
Hypertension ; Pulmonary CT ; High resolution heart defects ; Congenital
High-resolution computed tomography (HRCT) was carried out in 36 patients with congenital left-to-right shunt disease and 10 normal control subjects to assess the feasibility of CT in the evaluation of pulmonary hemodynamics. The patients had a left-to-right or a bidirectional shunt and the hemodynamic data obtained by cardiac catheterization in these patients were compared to the information obtained by CT imaging. The pulmonary/systemic blood flow (Q(p)/Q(s)) ratio and pulmonic/systemic resistance (R(p)/R(s)) ratio had a significant correlation with the pulmonary artery/bronchus (PA/Br) ratio (r = 0.54 and r = -0.37, respectively) and pulmonary vein/bronchus (PV/Br) ratio (r = 0.66 and r = -0.66, respectively), and the R(p)/R(s) and mean PA pressure also showed a significant correlation with the PA/PV ratio (r = 0.53 and r = -0.61, respectively) in the mid-lung field when accompanying bronchi were 4. 0-5.9 mm in diameter. There was no correlation between the hemodynamic data and the size of the central and hilar PA or with the rate of PA tapering. With HRCT, it is possible to evaluate pulmonary hemodynamics in patients with congenital heart disease with a left-to-right or bidirectional shunt, particularly R(p)/R(s) and mean PA pressure, which have been very difficult to obtain noninvasively. The small-sized pulmonary vessel/Br ratio or the small-sized PA/PV ratio could offer very useful information, but the dimension of the central PA provided the least useful information.
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1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Chang, Byung Chul(장병철)
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