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여성 급성 심근경색증 환자의 연령에 따른 임상 양상 및 장기 추적 경과 관찰.

Other Titles
 Age-Related Difference in Long-Term Prognosis of Acute Myocardial Infarction in Women 
Authors
 정보영  ;  하종원  ;  최동훈  ;  장양수  ;  안신기 임세중  ;  정남식  ;  심원흠  ;  조승연  ;  김성순 
Citation
 Korean Circulation Journal, Vol.30(10) : 1245-1256, 2000 
Journal Title
 Korean Circulation Journal 
ISSN
 1738-5520 
Issue Date
2000
Keywords
Acute myocardialinfarction ; Woman ; Prognosis ; Age
Abstract
Background and Objectives:The purpose of this study was to evaluate the age-related differences in clinical features, coronary anatomy, risk factors, hospital courses, and long-term prognosis of acute myocardial infarction (AMI) in women. Materials and Methods:Total 513 female patients with AMI were divided into 3 groups; group 1 (n=43, 50 years old or less), group 2 (n=302, between 51 years and 70 years old), and group 3 (n= 168, older than 70 years). Clinical follow-up including cardiac events was performed for mean duration of 26 months (1-155 months). Cardiac events include cardiac death, reinfarction, CABG, PTCA, CHF, stroke, and recurrent angina. Results:Minimal lesion (<50% stenosis) in infarct-related artery was more prevalent in group 1 than in group 3 (p<0.05). In group 2, the number of low high density lipoprotein (HDL) was significantly more than in group 3 (p<0.01). During hospitalization, death and shock were more prevalently observed in group 3 than group 1 (p<0.005) and group 2 (p<0.001). Group 3 had more heart failures than group 1 (p<0. 001) and group 2 (p<0.001) and group 2 had more heart failures than group 1 (p<0.05). The younger age group showed a significantly higher survial rate (7 years:group 1;76.1%, group 2;60.6%, group 3;34.2%, p<0. 0001, Log Rank Stat=49.4) and cardiac event-free survival rate (7 years:group 1; 48.4%, group 2; 32. 3%, group 3;16.0%, p<0.0001, Log Rank Stat=37.5) for each 3 comparisons. In Cox proportional harzard analysis, LV systolic function influenced the group 2 survival (odds ratio 3.8, 95% CI 1.7 to 8.3, p<0.005) and the group 3 survival (odds ratio 2.2, 95% CI 1.1 to 4.5, p<0.05). The cardiac event free survival was influenced by age (odds ratio 1.6, 95% CI 1.2 to 2.1, p<0.005) and LV systolic function (odds ratio 1.8, 95% CI 1.3 to 2.5, p<0.001). Conclusion:Younger female patients with AMI had a more favorable prognosis compared with older female patients. LV systolic fuction was important as a prognostic factor for long-term survival except younger female AMI patients. (Korean Circulation J 2000;30(10):1245-1256)
Files in This Item:
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Rim, Se Joong(임세중) ORCID logo https://orcid.org/0000-0002-7631-5581
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chung, Nam Sik(정남식)
Joung, Bo Young(정보영) ORCID logo https://orcid.org/0000-0001-9036-7225
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
Ha, Jong Won(하종원) ORCID logo https://orcid.org/0000-0002-8260-2958
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/171767
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