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Exercise therapy effect on natural killer cell cytotoxic activity in stomach cancer patients after curative surgery

DC FieldValueLanguage
dc.contributor.author윤동섭-
dc.date.accessioned2019-11-11T05:08:00Z-
dc.date.available2019-11-11T05:08:00Z-
dc.date.issued2000-
dc.identifier.issn0003-9993-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/171637-
dc.description.abstractOBJECTIVE: To evaluate the effect of early exercise therapy on the natural killer cell cytotoxic activity (NKCA) of patients who had undergone curative resection of stomach cancer. DESIGN: Prospective study. PATIENTS: Thirty-five stomach cancer patients who had undergone curative surgery were randomly divided into an exercise group (n = 17) and a control group (n = 18). INTERVENTION: From postoperative day 2, moderated exercise using arm and bicycle ergometers performed twice a day, 5 times a week, for 14 days. The intensity of exercise was 60% of maximal heart rate. Venous blood samples were obtained on postoperative days 1, 7, and 14. MAIN OUTCOME MEASURE: Mean sequential change of NKCA. RESULTS: The mean sequential change of NKCA decreased until postoperative day 7 and then increased. Mean NKCA of day 7 decreased in both groups, compared with that at postoperative day 1. At day 14, the mean NKCA of the exercise group demonstrated a significant increase compared with that of the control group (p < .05). CONCLUSION: This study suggests that early moderate exercise has a beneficial effect on the function of in vitro NK cells in stomach cancer patients after curative surgery.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherW.B. Saunders-
dc.relation.isPartOfArchives of Physical Medicine and Rehabilitation-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHExercise Therapy*-
dc.subject.MESHHumans-
dc.subject.MESHKiller Cells, Natural/metabolism*-
dc.subject.MESHLinear Models-
dc.subject.MESHLymphatic Metastasis-
dc.subject.MESHMiddle Aged-
dc.subject.MESHProspective Studies-
dc.subject.MESHStomach Neoplasms/immunology-
dc.subject.MESHStomach Neoplasms/surgery-
dc.subject.MESHStomach Neoplasms/therapy*-
dc.titleExercise therapy effect on natural killer cell cytotoxic activity in stomach cancer patients after curative surgery-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학교실)-
dc.contributor.googleauthorYoung-Moo Na-
dc.contributor.googleauthorMin-Young Kim-
dc.contributor.googleauthorYong-Kyun Kim-
dc.contributor.googleauthorYoung-Ran Ha-
dc.contributor.googleauthorDong Sup Yoon-
dc.identifier.doi10.1016/S0003-9993(00)90110-2-
dc.contributor.localIdA02548-
dc.relation.journalcodeJ00230-
dc.identifier.eissn1532-821X-
dc.identifier.pmid10857523-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0003999300901102-
dc.contributor.alternativeNameYoon, Dong Sup-
dc.contributor.affiliatedAuthor윤동섭-
dc.citation.volume81-
dc.citation.number6-
dc.citation.startPage777-
dc.citation.endPage779-
dc.identifier.bibliographicCitationArchives of Physical Medicine and Rehabilitation, Vol.81(6) : 777-779, 2000-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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