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Exercise therapy effect on natural killer cell cytotoxic activity in stomach cancer patients after curative surgery
DC Field | Value | Language |
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dc.contributor.author | 윤동섭 | - |
dc.date.accessioned | 2019-11-11T05:08:00Z | - |
dc.date.available | 2019-11-11T05:08:00Z | - |
dc.date.issued | 2000 | - |
dc.identifier.issn | 0003-9993 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171637 | - |
dc.description.abstract | OBJECTIVE: To evaluate the effect of early exercise therapy on the natural killer cell cytotoxic activity (NKCA) of patients who had undergone curative resection of stomach cancer. DESIGN: Prospective study. PATIENTS: Thirty-five stomach cancer patients who had undergone curative surgery were randomly divided into an exercise group (n = 17) and a control group (n = 18). INTERVENTION: From postoperative day 2, moderated exercise using arm and bicycle ergometers performed twice a day, 5 times a week, for 14 days. The intensity of exercise was 60% of maximal heart rate. Venous blood samples were obtained on postoperative days 1, 7, and 14. MAIN OUTCOME MEASURE: Mean sequential change of NKCA. RESULTS: The mean sequential change of NKCA decreased until postoperative day 7 and then increased. Mean NKCA of day 7 decreased in both groups, compared with that at postoperative day 1. At day 14, the mean NKCA of the exercise group demonstrated a significant increase compared with that of the control group (p < .05). CONCLUSION: This study suggests that early moderate exercise has a beneficial effect on the function of in vitro NK cells in stomach cancer patients after curative surgery. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | W.B. Saunders | - |
dc.relation.isPartOf | Archives of Physical Medicine and Rehabilitation | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Exercise Therapy* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Killer Cells, Natural/metabolism* | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Lymphatic Metastasis | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Stomach Neoplasms/immunology | - |
dc.subject.MESH | Stomach Neoplasms/surgery | - |
dc.subject.MESH | Stomach Neoplasms/therapy* | - |
dc.title | Exercise therapy effect on natural killer cell cytotoxic activity in stomach cancer patients after curative surgery | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Surgery (외과학교실) | - |
dc.contributor.googleauthor | Young-Moo Na | - |
dc.contributor.googleauthor | Min-Young Kim | - |
dc.contributor.googleauthor | Yong-Kyun Kim | - |
dc.contributor.googleauthor | Young-Ran Ha | - |
dc.contributor.googleauthor | Dong Sup Yoon | - |
dc.identifier.doi | 10.1016/S0003-9993(00)90110-2 | - |
dc.contributor.localId | A02548 | - |
dc.relation.journalcode | J00230 | - |
dc.identifier.eissn | 1532-821X | - |
dc.identifier.pmid | 10857523 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0003999300901102 | - |
dc.contributor.alternativeName | Yoon, Dong Sup | - |
dc.contributor.affiliatedAuthor | 윤동섭 | - |
dc.citation.volume | 81 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 777 | - |
dc.citation.endPage | 779 | - |
dc.identifier.bibliographicCitation | Archives of Physical Medicine and Rehabilitation, Vol.81(6) : 777-779, 2000 | - |
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