Cited 5 times in
Prognostic Implications of the Left Atrial Volume Index in Patients with Progressive Mitral Stenosis
DC Field | Value | Language |
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dc.contributor.author | 장혁재 | - |
dc.date.accessioned | 2019-10-28T02:04:37Z | - |
dc.date.available | 2019-10-28T02:04:37Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1975-4612 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171472 | - |
dc.description.abstract | BACKGROUND: Limited data are available on the prognosis of progressive mitral stenosis (MS). We evaluated the factors associated with adverse events in patients with progressive MS. METHODS: We retrospectively analyzed 259 consecutive patients with pure progressive MS with a mitral valve area (MVA) between 1.5 and 2.0 cm². The primary outcome measures were a composite endpoint of cardiac death, heart failure hospitalization, mitral valve surgery or percutaneous mitral valvuloplasty, and ischemic stroke. RESULTS: The mean patient age was 62 ± 12 years, and the mean MVA was 1.71 ± 0.15 cm². Over a median follow-up duration of 52 months, a total of 41 patients (18.3%) experienced the composite endpoint. In multivariable Cox regression analysis, prior stroke (hazard ratio [HR], 4.54; 95% confidence interval [CI], 2.16-9.54; p < 0.001) and left atrial volume index (LAVI) of > 50 mL/m² (HR, 4.45; 95% CI, 1.31-15.31; p = 0.017) were identified as independent predictors of the composite endpoint, even after adjusting for age and sex. Patients with a LAVI ≤ 50 mL/m² demonstrated favorable event-free survival compared with those with a LAVI > 50 mL/m² in either the overall population (p < 0.001) or asymptomatic patients (p = 0.002). Atrial fibrillation (AF), left ventricular mass index (LVMI), MVA, and mean diastolic pressure were factors independently associated with LAVI (all p < 0.05). CONCLUSIONS: A deleterious impact of a high LAVI on outcome was observed in patients with progressive MS. The LAVI was mainly influenced by the presence of AF, the severity of MS, and LVMI in this population. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | Korean, English | - |
dc.publisher | Korean Society of Echocardiography | - |
dc.relation.isPartOf | Journal of Cardiovascular Ultrasound | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Prognostic Implications of the Left Atrial Volume Index in Patients with Progressive Mitral Stenosis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | In-Jeong Cho | - |
dc.contributor.googleauthor | Hyeonju Jeong | - |
dc.contributor.googleauthor | Jah-Yeon Choi | - |
dc.contributor.googleauthor | Sang-Eun Lee | - |
dc.contributor.googleauthor | Hyuk-Jae Chang | - |
dc.identifier.doi | 10.4250/jcvi.2019.27.e20 | - |
dc.contributor.localId | A03490 | - |
dc.relation.journalcode | J01298 | - |
dc.identifier.eissn | 2005-9655 | - |
dc.identifier.pmid | 30993947 | - |
dc.subject.keyword | Left atrial volume | - |
dc.subject.keyword | Mitral stenosis | - |
dc.subject.keyword | Prognosis | - |
dc.contributor.alternativeName | Chang, Hyuck Jae | - |
dc.contributor.affiliatedAuthor | 장혁재 | - |
dc.citation.volume | 27 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 122 | - |
dc.citation.endPage | 133 | - |
dc.identifier.bibliographicCitation | Journal of Cardiovascular Ultrasound, Vol.27(2) : 122-133, 2019 | - |
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