13 21

Cited 0 times in

Prognostic Implications of the Left Atrial Volume Index in Patients with Progressive Mitral Stenosis

DC FieldValueLanguage
dc.contributor.author장혁재-
dc.date.accessioned2019-10-28T02:04:37Z-
dc.date.available2019-10-28T02:04:37Z-
dc.date.issued2019-
dc.identifier.issn1975-4612-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/171472-
dc.description.abstractBACKGROUND: Limited data are available on the prognosis of progressive mitral stenosis (MS). We evaluated the factors associated with adverse events in patients with progressive MS. METHODS: We retrospectively analyzed 259 consecutive patients with pure progressive MS with a mitral valve area (MVA) between 1.5 and 2.0 cm². The primary outcome measures were a composite endpoint of cardiac death, heart failure hospitalization, mitral valve surgery or percutaneous mitral valvuloplasty, and ischemic stroke. RESULTS: The mean patient age was 62 ± 12 years, and the mean MVA was 1.71 ± 0.15 cm². Over a median follow-up duration of 52 months, a total of 41 patients (18.3%) experienced the composite endpoint. In multivariable Cox regression analysis, prior stroke (hazard ratio [HR], 4.54; 95% confidence interval [CI], 2.16-9.54; p < 0.001) and left atrial volume index (LAVI) of > 50 mL/m² (HR, 4.45; 95% CI, 1.31-15.31; p = 0.017) were identified as independent predictors of the composite endpoint, even after adjusting for age and sex. Patients with a LAVI ≤ 50 mL/m² demonstrated favorable event-free survival compared with those with a LAVI > 50 mL/m² in either the overall population (p < 0.001) or asymptomatic patients (p = 0.002). Atrial fibrillation (AF), left ventricular mass index (LVMI), MVA, and mean diastolic pressure were factors independently associated with LAVI (all p < 0.05). CONCLUSIONS: A deleterious impact of a high LAVI on outcome was observed in patients with progressive MS. The LAVI was mainly influenced by the presence of AF, the severity of MS, and LVMI in this population.-
dc.description.statementOfResponsibilityopen-
dc.languageKorean, English-
dc.publisherKorean Society of Echocardiography-
dc.relation.isPartOfJournal of Cardiovascular Ultrasound-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.titlePrognostic Implications of the Left Atrial Volume Index in Patients with Progressive Mitral Stenosis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorIn-Jeong Cho-
dc.contributor.googleauthorHyeonju Jeong-
dc.contributor.googleauthorJah-Yeon Choi-
dc.contributor.googleauthorSang-Eun Lee-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.identifier.doi10.4250/jcvi.2019.27.e20-
dc.contributor.localIdA03490-
dc.relation.journalcodeJ01298-
dc.identifier.eissn2005-9655-
dc.identifier.pmid30993947-
dc.subject.keywordLeft atrial volume-
dc.subject.keywordMitral stenosis-
dc.subject.keywordPrognosis-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.affiliatedAuthor장혁재-
dc.citation.volume27-
dc.citation.number2-
dc.citation.startPage122-
dc.citation.endPage133-
dc.identifier.bibliographicCitationJournal of Cardiovascular Ultrasound, Vol.27(2) : 122-133, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.