Cited 11 times in
Bone Regeneration Effect of Hyperbaric Oxygen Therapy Duration on Calvarial Defects in Irradiated Rats
DC Field | Value | Language |
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dc.contributor.author | 박영범 | - |
dc.contributor.author | 박원서 | - |
dc.contributor.author | 정문규 | - |
dc.date.accessioned | 2019-10-28T01:50:11Z | - |
dc.date.available | 2019-10-28T01:50:11Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 2314-6133 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171359 | - |
dc.description.abstract | Objective: In this study, we evaluated changes in bone remodeling in an irradiated rat calvarial defect model according to duration of hyperbaric oxygen therapy. Materials and Methods: The 28 rats were divided into four groups. Radiation of 12 Gy was applied to the skull, and 5-mm critical size defects were formed on both sides of the skull. Bone grafts were applied to one side of formed defects. From the day after surgery, HBO was applied for 0, 1, and 3 weeks. At 6 weeks after bone graft, experimental sites were removed and analyzed for radiography, histology, and histomorphometry. Results: Micro-CT analysis showed a significant increase in new bone volume in the HBO-3 group, with or without bone graft. When bone grafting was performed, BV, BS, and BS/TV all significantly increased. Histomorphometric analysis showed significant increases in %NBA and %BVN in the HBO-1 and HBO-3 groups, regardless of bone graft. Conclusion: Hyperbaric oxygen therapy was effective for bone regeneration with only 1 week of treatment. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Hindawi Pub. Co. | - |
dc.relation.isPartOf | BioMed Research International | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Bone Regeneration/radiation effects* | - |
dc.subject.MESH | Hyperbaric Oxygenation* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Radiation Injuries, Experimental*/diagnostic imaging | - |
dc.subject.MESH | Radiation Injuries, Experimental*/metabolism | - |
dc.subject.MESH | Radiation Injuries, Experimental*/pathology | - |
dc.subject.MESH | Radiation Injuries, Experimental*/therapy | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.subject.MESH | Skull*/diagnostic imaging | - |
dc.subject.MESH | Skull*/injuries | - |
dc.subject.MESH | Skull*/metabolism | - |
dc.subject.MESH | Skull*/pathology | - |
dc.subject.MESH | X-Ray Microtomography | - |
dc.subject.MESH | X-Rays/adverse effects* | - |
dc.title | Bone Regeneration Effect of Hyperbaric Oxygen Therapy Duration on Calvarial Defects in Irradiated Rats | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Prosthodontics (보철과학교실) | - |
dc.contributor.googleauthor | Kyeong-Mee Park | - |
dc.contributor.googleauthor | Changdae Kim | - |
dc.contributor.googleauthor | Wonse Park | - |
dc.contributor.googleauthor | Young-Bum Park | - |
dc.contributor.googleauthor | Moon-Kyu Chung | - |
dc.contributor.googleauthor | Sungtae Kim | - |
dc.identifier.doi | 10.1155/2019/9051713 | - |
dc.contributor.localId | A01567 | - |
dc.contributor.localId | A01589 | - |
dc.contributor.localId | A03600 | - |
dc.relation.journalcode | J00315 | - |
dc.identifier.eissn | 2314-6141 | - |
dc.identifier.pmid | 31061829 | - |
dc.contributor.alternativeName | Park, Young Bum | - |
dc.contributor.affiliatedAuthor | 박영범 | - |
dc.contributor.affiliatedAuthor | 박원서 | - |
dc.contributor.affiliatedAuthor | 정문규 | - |
dc.citation.volume | 2019 | - |
dc.citation.startPage | 9051713 | - |
dc.identifier.bibliographicCitation | BioMed Research International, Vol.2019 : 9051713, 2019 | - |
dc.identifier.rimsid | 64355 | - |
dc.type.rims | ART | - |
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