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Role of proteases, cytokines, and growth factors in bone invasion by oral squamous cell carcinoma
DC Field | Value | Language |
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dc.contributor.author | 정원윤 | - |
dc.contributor.author | 손승화 | - |
dc.date.accessioned | 2019-09-20T07:53:57Z | - |
dc.date.available | 2019-09-20T07:53:57Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1226-7155 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/171106 | - |
dc.description.abstract | Oral squamous cell carcinoma (OSCC) is the most common oral malignancy and an increasing global public health problem. OSCC frequently invades the jaw bone. OSCC-induced bone invasion has a significant impact on tumor stage, treatment selection, patient outcome, and quality of life. A number of studies have shown that osteoclast-mediated bone resorption is a major step in the progression of bone invasion by OSCC; however, the molecular mechanisms involved in OSCC bone invasion are not yet clear. In this review, we present the clinical types of OSCC bone invasion and summarize the role of key molecules, including proteases, cytokines, and growth factors, in the sequential process of bone invasion. A better understanding of bone invasion will facilitate the discovery of molecular targets for early detection and treatment of OSCC bone invasion. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Harn Rim Won Printing Co. | - |
dc.relation.isPartOf | International Journal of Oral Biology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Role of proteases, cytokines, and growth factors in bone invasion by oral squamous cell carcinoma | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Oral Biology (구강생물학교실) | - |
dc.contributor.googleauthor | Seung Hwa Son | - |
dc.contributor.googleauthor | Won-Yoon Chung | - |
dc.identifier.doi | 10.11620/IJOB.2019.44.2.37 | - |
dc.contributor.localId | A03676 | - |
dc.relation.journalcode | J01144 | - |
dc.subject.keyword | Role of proteases | - |
dc.subject.keyword | cytokines | - |
dc.subject.keyword | and growth factors in bone invasion by oral squamous cell carcinoma | - |
dc.contributor.alternativeName | Chung, Won Yoon | - |
dc.contributor.affiliatedAuthor | 정원윤 | - |
dc.citation.volume | 44 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 37 | - |
dc.citation.endPage | 42 | - |
dc.identifier.bibliographicCitation | International Journal of Oral Biology, Vol.44(2) : 37-42, 2019 | - |
dc.identifier.rimsid | 64885 | - |
dc.type.rims | ART | - |
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