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Refractive Outcomes of 4-Year-old Children after Intravitreal Anti-vascular Endothelial Growth Factor versus Laser Photocoagulation for Retinopathy of Prematurity
DC Field | Value | Language |
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dc.contributor.author | 강현구 | - |
dc.contributor.author | 한승한 | - |
dc.contributor.author | 한진우 | - |
dc.date.accessioned | 2019-09-20T07:39:38Z | - |
dc.date.available | 2019-09-20T07:39:38Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1011-8942 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/170999 | - |
dc.description.abstract | PURPOSE: To compare long-term refractive outcomes associated with intravitreal anti-vascular endothelial growth factor (VEGF) versus laser photocoagulation treatment for retinopathy of prematurity (ROP). METHODS: A total of 52 eyes from 27 ROP patients treated at two tertiary referral-based hospitals from August 2006 to December 2013 were reviewed. The primary outcome was refractive error measured at the age of 4 years, accounting for within-patient inter-eye correlation. Secondary outcomes included the recurrence rate and treatment complications. RESULTS: The mean age at refraction was 4.7 ± 0.3 years in the laser group (n = 30) and 4.4 ± 0.3 years in the anti-VEGF group (n = 22). No significant differences were noted in gestational age, birthweight, post-menstrual age at treatment, or ROP stage/zone distribution between groups. Mean spherical equivalent was also not significantly different (-1.0 diopters in the laser group and -0.3 diopters in the injection group, p = 0.603). Clustered regression analysis revealed that only gestational age was significantly correlated with mean spherical equivalent (p < 0.001; 95% confidence interval, -0.007 to -0.002). Recurrence was noted in four eyes (13.3%) in the laser group, but this difference was not significant (p = 0.128). There were no major systemic complications reported in either group. CONCLUSIONS: Treatment type, whether laser or anti-VEGF injection, does not appear to influence long-term refractive outcomes in ROP. Concern regarding refractive outcomes should not be the most important factor when selecting ROP treatment modality. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | KJO | - |
dc.relation.isPartOf | Korean Journal of Ophthalmology | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.title | Refractive Outcomes of 4-Year-old Children after Intravitreal Anti-vascular Endothelial Growth Factor versus Laser Photocoagulation for Retinopathy of Prematurity | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학교실) | - |
dc.contributor.googleauthor | Hyun Goo Kang | - |
dc.contributor.googleauthor | Tae Young Kim | - |
dc.contributor.googleauthor | Jinu Han | - |
dc.contributor.googleauthor | Sueng-Han Han | - |
dc.identifier.doi | 10.3341/kjo.2019.0011 | - |
dc.contributor.localId | A04873 | - |
dc.contributor.localId | A04303 | - |
dc.contributor.localId | A04329 | - |
dc.relation.journalcode | J02931 | - |
dc.identifier.eissn | 2092-9382 | - |
dc.identifier.pmid | 31179659 | - |
dc.subject.keyword | Intravitreal injections | - |
dc.subject.keyword | Laser therapy | - |
dc.subject.keyword | Refractive errors | - |
dc.subject.keyword | Retinopathy of prematurity | - |
dc.subject.keyword | Vascular endothelial growth factor A | - |
dc.contributor.alternativeName | Kang, Hyun Goo | - |
dc.contributor.affiliatedAuthor | 강현구 | - |
dc.contributor.affiliatedAuthor | 한승한 | - |
dc.contributor.affiliatedAuthor | 한진우 | - |
dc.citation.volume | 33 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 272 | - |
dc.citation.endPage | 278 | - |
dc.identifier.bibliographicCitation | Korean Journal of Ophthalmology, Vol.33(3) : 272-278, 2019 | - |
dc.identifier.rimsid | 64555 | - |
dc.type.rims | ART | - |
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