Cited 11 times in
Borderline high serum calcium levels are associated with arterial stiffness and 10-year cardiovascular disease risk determined by Framingham risk score
DC Field | Value | Language |
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dc.contributor.author | 박병진 | - |
dc.contributor.author | 이용제 | - |
dc.date.accessioned | 2019-07-23T06:58:57Z | - |
dc.date.available | 2019-07-23T06:58:57Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 1524-6175 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/170406 | - |
dc.description.abstract | Recent epidemiological data indicate that the concentration of circulatingcalciumis related tocardiovasculardisease(CVD) mortality. Wedeterminedwhetherserumcalciumlevel is related toarterialstiffnessand10-yearCVDriskcalculated byFraminghamriskscore(FRS). We examined the association of normal-rangeserumcalciumlevel witharterialstiffnessand FRS in 565 Korean adults participating at the Health Promotion Center of Gangnam Severance Hospital between March 2016 and May 2017.Highbrachial-ankle pulse wave velocity (baPWV) was defined as >1460cm/s, andhighFRS was defined as ≥10 percent for10-yearCVDrisk. Odds ratios (ORs) and 95% confidence intervals (95% CIs) forhighbaPWV andhighFRS were calculated using multiple logistic regression analysis after adjusting for confounding variables. The OR (95% CI) forhighbaPWV was 3.91 (1.15-7.36) per 1mg/dL increment ofserumcalciumafter adjusting for age, sex, body mass index, smoking status, exercise regularity, alcohol consumption, mean blood pressure, fasting plasma glucose, triglyceride, HDL-cholesterol, C-reactive protein, γ-glutamyltransferase, uric acid level, phosphate level, potassium level, and presence of hypertension, diabetes and dyslipidemia medications (P=0.024). A positive association betweenserumcalciumlevel andhighFRS was also observed after adjusting for the same covariables (OR, 3.54 [95% CI, 1.01-12.44], P=0.048).Serumcalciumlevel was independently and positivelyassociatedwith baPWV and10-yearCVDriskestimates. Early detection of higherserumcalciumlevel may be important for the assessment ofarterialstiffnessand futureriskof acardiovascularevent. | - |
dc.description.statementOfResponsibility | open | - |
dc.language | English | - |
dc.publisher | Wiley Periodicals Inc. | - |
dc.relation.isPartOf | JOURNAL OF CLINICAL HYPERTENSION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Borderline high serum calcium levels are associated with arterial stiffness and 10-year cardiovascular disease risk determined by Framingham risk score | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학교실) | - |
dc.contributor.googleauthor | Byoungjin Park | - |
dc.contributor.googleauthor | Yong-Jae Lee | - |
dc.identifier.doi | 10.1111/jch.13532 | - |
dc.contributor.localId | A01477 | - |
dc.contributor.localId | A02982 | - |
dc.relation.journalcode | J01320 | - |
dc.identifier.eissn | 1751-7176 | - |
dc.identifier.pmid | 30941878 | - |
dc.subject.keyword | Framinghamriskscore | - |
dc.subject.keyword | arterialstiffness | - |
dc.subject.keyword | cardiovasculardisease | - |
dc.subject.keyword | pulse wave velocity | - |
dc.subject.keyword | serumcalcium | - |
dc.contributor.alternativeName | Park, Byoung Jin | - |
dc.contributor.affiliatedAuthor | 박병진 | - |
dc.contributor.affiliatedAuthor | 이용제 | - |
dc.citation.volume | 21 | - |
dc.citation.number | 5 | - |
dc.citation.startPage | 668 | - |
dc.citation.endPage | 673 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CLINICAL HYPERTENSION, Vol.21(5) : 668-673, 2019 | - |
dc.identifier.rimsid | 62089 | - |
dc.type.rims | ART | - |
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