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A periodic comparison of the survival and prognostic factors of biliary atresia after Kasai portoenterostomy: a single-center study in Korea

DC FieldValueLanguage
dc.contributor.author고홍-
dc.contributor.author이동은-
dc.contributor.author인경-
dc.contributor.author한석주-
dc.contributor.author호인걸-
dc.date.accessioned2019-07-23T06:57:49Z-
dc.date.available2019-07-23T06:57:49Z-
dc.date.issued2019-
dc.identifier.issn0179-0358-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/170394-
dc.description.abstractPURPOSE: We explored the chronologic changes in prognostic factors and clinical outcomes of Kasai portoenterostomy (KPE) for biliary atresia (BA). METHODS: Patients undergoing KPE between 1997 and 2016 were analyzed retrospectively. Ninety-two consecutive patients who underwent KPE from 1997 to 2006 (Era 1) were compared with 150 patients who underwent KPE from 2007 to 2016 (Era 2) for clinical outcomes and prognostic factors. RESULTS: The jaundice clearance rate increased by 8.8% (66.7% vs. 75.5% for Eras 1 and 2, respectively, p = 0.180), and the 5-year native liver survival (NLS) rate improved slightly (62.5% vs. 64.0% for Eras 1 and 2, respectively, p = 0.617) in Era 2. The hazard ratio for age at KPE (≥ 90 days) with regard to 5-year NLS and the odds ratio for age at KPE (< 90 days) with regard to jaundice clearance were both lower in Era 2 than in Era 1 (1.95 vs. 2.25 and 2.67 vs. 5.21, respectively). CONCLUSION: The clinical outcomes improved over a period in a single surgeon's practice. We demonstrated that the impact of age at the time of KPE on operative outcomes became less significant over time with the increase in the single surgeon's experience and improvement in medical treatment for BA.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSpringer International-
dc.relation.isPartOfPEDIATRIC SURGERY INTERNATIONAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHBiliary Atresia/diagnosis-
dc.subject.MESHBiliary Atresia/mortality-
dc.subject.MESHBiliary Atresia/surgery-
dc.subject.MESHChild, Preschool-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHInfant-
dc.subject.MESHMale-
dc.subject.MESHPortoenterostomy, Hepatic/methods-
dc.subject.MESHPrognosis-
dc.subject.MESHRepublic of Korea/epidemiology-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHSurvival Rate/trends-
dc.titleA periodic comparison of the survival and prognostic factors of biliary atresia after Kasai portoenterostomy: a single-center study in Korea-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Pediatrics (소아청소년과학교실)-
dc.contributor.googleauthorKyong Ihn-
dc.contributor.googleauthorYounghyun Na-
dc.contributor.googleauthorIn Geol Ho-
dc.contributor.googleauthorDongeun Lee-
dc.contributor.googleauthorHong Koh-
dc.contributor.googleauthorSeok Joo Han-
dc.identifier.doi10.1007/s00383-018-04434-5-
dc.contributor.localIdA00156-
dc.contributor.localIdA05489-
dc.contributor.localIdA05489-
dc.contributor.localIdA05505-
dc.contributor.localIdA05505-
dc.contributor.localIdA04288-
dc.contributor.localIdA04288-
dc.contributor.localIdA04706-
dc.contributor.localIdA04706-
dc.relation.journalcodeJ02494-
dc.identifier.eissn1437-9813-
dc.identifier.pmid30607544-
dc.identifier.urlhttps://link.springer.com/article/10.1007%2Fs00383-018-04434-5-
dc.subject.keywordBiliary atresia-
dc.subject.keyword Kasai portoenterostomy-
dc.subject.keywordLiver fibrosis-
dc.subject.keywordNative liver survival-
dc.subject.keywordPrognosis-
dc.contributor.alternativeNameKoh, Hong-
dc.contributor.affiliatedAuthor고홍-
dc.contributor.affiliatedAuthor이동은-
dc.contributor.affiliatedAuthor이동은-
dc.contributor.affiliatedAuthor인경-
dc.contributor.affiliatedAuthor인경-
dc.contributor.affiliatedAuthor한석주-
dc.contributor.affiliatedAuthor한석주-
dc.contributor.affiliatedAuthor호인걸-
dc.contributor.affiliatedAuthor호인걸-
dc.citation.volume35-
dc.citation.number3-
dc.citation.startPage285-
dc.citation.endPage292-
dc.identifier.bibliographicCitationPEDIATRIC SURGERY INTERNATIONAL, Vol.35(3) : 285-292, 2019-
Appears in Collections:
7. Others (기타) > Gangnam Severance Hospital (강남세브란스병원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers

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