259 541

Cited 7 times in

Subcutaneous Immunotherapy in Patients with Fagales Pollen-Induced Oral Allergy Syndrome

Authors
 Nasil Kong  ;  Sunyoung Kim  ;  Sang Chul Lee  ;  Kyung Hee Park  ;  Jae-Hyun Lee  ;  Jung-Won Park 
Citation
 YONSEI MEDICAL JOURNAL, Vol.60(4) : 389-394, 2019 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2019
MeSH
Adolescent ; Adult ; Allergens ; Fagales/chemistry ; Female ; Food Hypersensitivity/therapy ; Humans ; Immunotherapy/methods ; Injections, Subcutaneous ; Male ; Middle Aged ; Plant Extracts/administration & dosage ; Plant Extracts/immunology ; Pollen/immunology ; Republic of Korea ; Surveys and Questionnaires ; Treatment Outcome
Keywords
Fagalespollen ; Oralallergysyndrome ; subcutaneousimmunotherapy
Abstract
Oralallergysyndrome(OAS) is the most common foodallergy-related condition in adults. This study aimed to investigate whethersubcutaneousimmunotherapy(SCIT) withFagalespollen-containing extracts can improve the clinical symptoms of OAS in Korea. In total, 56 OASpatientswere included: 19 subjects treated with SCIT, which includedFagalespollen extracts, and 37 not treated withimmunotherapy(IT). We reviewed thepatients' medical records and administered a telephone questionnaire at one point to assess baseline OAS features and changes in thepatients' OAS and allergic rhinoconjunctivitis (ARC) symptoms after treatment. Only 12patientswho received SCIT and 15patientsthat did not receive SCIT could report on changes in OAS symptoms after treatment because the otherpatientspracticed strict avoidance of their culprit fruits and vegetables, and they could not respond to the status of OAS. SCIT reduced the severity of OAS (p=0.005). Nine of the 12patients(75%) that received SCIT reported a more than 50% reduction in OAS symptoms. In contrast, only three of the 15patients(20%) that did not receive IT reported more than a 50% reduction in OAS symptoms. SCIT also reduced the severity of ARC symptoms (p<0.001). The results indicate that SCIT withFagalespollen-containing extracts is associated with improved OAS symptoms in Korea.
Files in This Item:
T201901934.pdf Download
DOI
10.3349/ymj.2019.60.4.389
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Kyung Hee(박경희) ORCID logo https://orcid.org/0000-0003-3605-5364
Park, Jung Won(박중원) ORCID logo https://orcid.org/0000-0003-0249-8749
Lee, Sang Chul(이상철)
Lee, Jae Hyun(이재현) ORCID logo https://orcid.org/0000-0002-0760-0071
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/170234
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links