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Comparative study of peritoneal dialysis versus hemodialysis on the clinical outcomes in Korea: a population-based approach

Authors
 Sung Woo Lee  ;  Na Rae Lee  ;  Soo Kyung Son  ;  Jimin Kim  ;  Ah Ram Sul  ;  Yunjung Kim  ;  Jung Tak Park  ;  Jung Pyo Lee  ;  Dong-Ryeol Ryu 
Citation
 Scientific Reports, Vol.9(1) : 5905, 2019 
Journal Title
 Scientific Reports 
Issue Date
2019
Abstract
There has been paucity of data regarding the secular trend of adverse outcomes in peritoneal dialysis (PD) as compared with hemodialysis(HD) in Korea. 96,596 patients who started dialysis between 2004-2015 in Korea were identified using the National Health Insurance Service database. The adjusted hazard ratio (HR) (95% confidence interval, CI) of PD over HD for mortality was 1.31 (1.27-1.36; P < 0.001) in the period of 2004-2007 and 1.21 (1.16-1.27; P < 0.001) in the period of 2008-2011. However, the hazard of PD over HD for mortality turned out to be insignificant in the period of 2012-2015. Similar trend was noted for nonfatal cardiovascular events (CVEs). In subgroup analysis, the hazard of PD over HD for mortality was evident, regardless of the status of age, diabetes, and comorbidity burden in 2004-2011. In 2012-2015, however, the hazard of PD over HD for mortality was insignificant when follow up was censored at one year, which became significant when follow up follow up was censored at three or five year. In conclusion, the mortality of PD over HD in Korea has been significantly improved, a finding that was paralleled by the improved nonfatal CVEs.
Files in This Item:
T201901930.pdf Download
DOI
10.1038/s41598-019-42508-z
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Park, Jung Tak(박정탁) ORCID logo https://orcid.org/0000-0002-2325-8982
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/170230
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