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Clinical feasibility of catheter-directed selective intracoronary computed tomography angiography using an extremely low dose of iodine in patients with coronary artery disease

DC Field Value Language
dc.contributor.author심학준-
dc.contributor.author이병권-
dc.contributor.author장양수-
dc.contributor.author장혁재-
dc.contributor.author홍영택-
dc.date.accessioned2019-07-11T03:32:24Z-
dc.date.available2019-07-11T03:32:24Z-
dc.date.issued2019-
dc.identifier.issn0938-7994-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/170023-
dc.description.abstractOBJECTIVE: This study aimed to evaluate the clinical feasibility of catheter-directed selective computed tomography angiography (S-CTA) in patients with coronary artery disease (CAD). METHODS: We prospectively enrolled 65 patients diagnosed with CAD who underwent conventional computed tomography angiography (C-CTA). C-CTA was performed with 60-90 mL of contrast medium (370 mg iodine/mL), whereas S-CTA was performed with 15 mL of contrast medium and 17.19 mg iodine/mL. Luminal enhancement range, homogeneity of luminal enhancement, image quality, plaque volume (PV), and percent aggregate plaque volume (%APV) were measured. Paired Student's t test, Wilcoxon rank-sum test, and Pearson's correlation coefficient were used to compare two methods. RESULTS: Luminal enhancement was significantly higher on S-CTA than on C-CTA (324.4 ± 8.0 Hounsfield unit (HU) vs. 312.0 ± 8.0 HU, p < 0.0001 in the per-vessel analysis). Transluminal attenuation gradient showed a significantly slower reduction pattern on S-CTA than on C-CTA (-0.65 HU/10 mm vs. -0.89 HU/10 mm, p < 0.0001 in the per-vessel analysis). Image noise was significantly lower on S-CTA than on C-CTA (39.6 ± 10.0 HU vs. 43.9 ± 9.4 HU, p < 0.0001). There was excellent correlation between S-CTA and C-CTA with respect to PV and %APV (r = 0.99, r = 0.98, respectively). CONCLUSIONS: S-CTA might be useful in facilitating atherosclerotic plaque analysis and providing guidance for complex lesions such as chronic total occlusion, particularly in cases in which on-site procedure planning is required. KEY POINTS: • Selective computed tomography angiography (S-CTA) can serve as an intraprocedural computed tomography angiography protocol. • S-CTA was performed with low dose of iodine compared with conventional computed tomography angiography. • S-CTA enables on-site atherosclerotic plaque analysis.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherSpringer International-
dc.relation.isPartOfEUROPEAN RADIOLOGY-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHCardiac Catheterization/methods*-
dc.subject.MESHComputed Tomography Angiography/methods*-
dc.subject.MESHContrast Media/administration & dosage-
dc.subject.MESHCoronary Angiography/methods*-
dc.subject.MESHCoronary Artery Disease/diagnosis*-
dc.subject.MESHFeasibility Studies-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHIodine/administration & dosage*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPlaque, Atherosclerotic/diagnosis*-
dc.titleClinical feasibility of catheter-directed selective intracoronary computed tomography angiography using an extremely low dose of iodine in patients with coronary artery disease-
dc.typeArticle-
dc.contributor.collegeResearch Institutes (연구소)-
dc.contributor.departmentYonsei Cardiovascular Research Institute (심혈관연구소)-
dc.contributor.googleauthorYoungtaek Hong-
dc.contributor.googleauthorHyung-Bok Park-
dc.contributor.googleauthorByoung Kwon Lee-
dc.contributor.googleauthorSeongmin Ha-
dc.contributor.googleauthorYeonggul Jang-
dc.contributor.googleauthorByunghwan Jeon-
dc.contributor.googleauthorSunghee Jung-
dc.contributor.googleauthorHackjoon Shim-
dc.contributor.googleauthorYang Soo Jang-
dc.contributor.googleauthorHyuk-Jae Chang-
dc.identifier.doi10.1007/s00330-018-5752-0-
dc.contributor.localIdA02215-
dc.contributor.localIdA02793-
dc.contributor.localIdA03448-
dc.contributor.localIdA03490-
dc.contributor.localIdA05736-
dc.relation.journalcodeJ00851-
dc.identifier.eissn1432-1084-
dc.identifier.pmid30421011-
dc.identifier.urlhttps://link.springer.com/article/10.1007%2Fs00330-018-5752-0-
dc.subject.keywordAtherosclerotic plaque-
dc.subject.keywordCardiac imaging technique-
dc.subject.keywordContrast media-
dc.subject.keywordCoronary angiography-
dc.subject.keywordCoronary arteries-
dc.contributor.alternativeNameShim, Hack Joon-
dc.contributor.affiliatedAuthor심학준-
dc.contributor.affiliatedAuthor이병권-
dc.contributor.affiliatedAuthor장양수-
dc.contributor.affiliatedAuthor장혁재-
dc.contributor.affiliatedAuthor홍영택-
dc.citation.volume29-
dc.citation.number5-
dc.citation.startPage2218-
dc.citation.endPage2225-
dc.identifier.bibliographicCitationEUROPEAN RADIOLOGY, Vol.29(5) : 2218-2225, 2019-
dc.identifier.rimsid62155-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Research Institute (부설연구소) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

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