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Development and validation of the Vitiligo Extent Score for a Target Area (VESTA) to assess the treatment response of a target lesion

Authors
 Jung Min Bae  ;  Sang Ho Oh  ;  Hee Young Kang  ;  Young Wook Ryoo  ;  Cheng‐Che E. Lan  ;  Lei‐Hong Xiang  ;  Ki‐Ho Kim  ;  Tamio Suzuki  ;  Ichiro Katayama  ;  Seung‐Chul Lee 
Citation
 PIGMENT CELL & MELANOMA RESEARCH, Vol.32(2) : 315-319, 2019 
Journal Title
 PIGMENT CELL & MELANOMA RESEARCH 
ISSN
 1755-1471 
Issue Date
2019
Keywords
measurement ; outcome ; target lesion ; treatment response ; validation ; vitiligo
Abstract
Since localized treatment for vitiligo is as essential as systemic treatment, a reliable instrument for target evaluation is needed besides those for whole body evaluation. We developed the Vitiligo Extent Score for a Target Area (VESTA) using reference images of both marginal and perifollicular repigmentation to measure the repigmentation rate (%) in a target lesion. In the validation study, a total of 65 dermatologists in 10 institutes evaluated 17 pairs of vitiligo images (pre- and post-treatment) using both a rough estimate and the VESTA. The VESTA (concordance correlation coefficient: 0.949, 95% confidence interval [CI] 0.942-0.955) was significantly more accurate than the rough estimate (0.896, 95% CI: 0.883-0.908). It was also associated with better inter-rater reliability over the rough estimate, albeit not significant. The VESTA can afford intuitive, convenient, and reliable assessment of the treatment response in a target area, and would be useful in clinical practice as well as retrospective studies.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1111/pcmr.12730
DOI
10.1111/pcmr.12730
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
Yonsei Authors
Oh, Sang Ho(오상호) ORCID logo https://orcid.org/0000-0002-4477-1400
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/169934
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