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Immediate versus early coronary angiography with targeted temperature management in out-of-hospital cardiac arrest survivors without ST-segment elevation: A propensity score-matched analysis from a multicenter registry

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dc.contributor.author박유석-
dc.date.accessioned2019-07-11T03:16:52Z-
dc.date.available2019-07-11T03:16:52Z-
dc.date.issued2019-
dc.identifier.issn0300-9572-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/169903-
dc.description.abstractAIM: The optimal coronary angiography (CAG) timing in out-of-hospital cardiac arrest (OHCA) survivors without ST-segment elevation (STE) for good neurologic outcome remains unknown. This study aimed to evaluate whether immediate versus early CAG impacts neurological outcomes of OHCA survivors without STE. METHODS: This multicenter retrospective observational registry-based study was conducted at the emergency department (ED) of 8 Korean tertiary care hospitals. Data of adult non-traumatic OHCA patients with no obvious extra-cardiac cause, without STE, who were treated with targeted temperature management (TTM), and in whom CAG was performed within 24 h after return of spontaneous circulation between 2010 and 2015 were extracted. Patients in the immediate (≤2 h) and early (2-24 h) CAG groups were propensity score matched. The primary endpoint was 1-month good neurological outcomes. RESULTS: Among 346 patients with TTM and CAG, 119 who underwent CAG after 24 h were excluded, leaving 112 and 115 in the immediate and early CAG groups, respectively. Median time to CAG was 120.0 (70.0-224.0) minutes; 97 (42.7%) patients had significant coronary artery stenosis. Good neurological outcome was higher in the early versus immediate CAG group (50.4% vs. 31.3%, P = 0.003), but no significant intergroup difference persisted after matching. CAG timing was not associated with good neurological outcomes (odds ratio, 1.917; 95% confidence interval, 0.954-3.852; P = 0.07). CONCLUSIONS: Coronary artery stenosis was found in 42.7% of TTM-treated non-STE OHCA patients with CAG within 24 h, but there was no clear neurological benefit of immediate versus early CAG.-
dc.description.statementOfResponsibilityrestriction-
dc.languageEnglish-
dc.publisherElsevier/north-Holland Biomedical Press-
dc.relation.isPartOfRESUSCITATION-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleImmediate versus early coronary angiography with targeted temperature management in out-of-hospital cardiac arrest survivors without ST-segment elevation: A propensity score-matched analysis from a multicenter registry-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Emergency Medicine (응급의학교실)-
dc.contributor.googleauthorYoun-Jung Kim-
dc.contributor.googleauthorYong Hwan Kim-
dc.contributor.googleauthorByung Kook Lee-
dc.contributor.googleauthorYoo Seok Park-
dc.contributor.googleauthorMin Seob Sim-
dc.contributor.googleauthorSu Jin Kim-
dc.contributor.googleauthorSang Hoon Oh-
dc.contributor.googleauthorDong Hoon Lee-
dc.contributor.googleauthorWon Young Kim-
dc.identifier.doi10.1016/j.resuscitation.2018.12.011-
dc.contributor.localIdA01592-
dc.relation.journalcodeJ02620-
dc.identifier.eissn1873-1570-
dc.identifier.pmid30576785-
dc.identifier.urlhttps://www.sciencedirect.com/science/article/pii/S0300957218310074-
dc.subject.keywordCardiopulmonary resuscitation-
dc.subject.keywordCoronary angiography-
dc.subject.keywordOut-of-hospital cardiac arrest-
dc.subject.keywordOutcome-
dc.subject.keywordPercutaneous coronary intervention-
dc.contributor.alternativeNamePark, Yoo Seok-
dc.contributor.affiliatedAuthor박유석-
dc.citation.volume135-
dc.citation.startPage30-
dc.citation.endPage36-
dc.identifier.bibliographicCitationRESUSCITATION, Vol.135 : 30-36, 2019-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Emergency Medicine (응급의학교실) > 1. Journal Papers

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