Cited 24 times in
COMPARISON OF SHORT-TERM EFFICACY BETWEEN ORAL SPIRONOLACTONE TREATMENT AND PHOTODYNAMIC THERAPY FOR THE TREATMENT OF NONRESOLVING CENTRAL SEROUS CHORIORETINOPATHY
DC Field | Value | Language |
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dc.contributor.author | 이성철 | - |
dc.contributor.author | 이승규 | - |
dc.contributor.author | 이지환 | - |
dc.date.accessioned | 2019-07-11T03:07:25Z | - |
dc.date.available | 2019-07-11T03:07:25Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0275-004X | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/169847 | - |
dc.description.abstract | PURPOSE: To compare the short-term therapeutic efficacy of oral spironolactone treatment with that of half-dose photodynamic therapy (PDT) in patients with nonresolving central serous chorioretinopathy. METHODS: This retrospective, interventional, comparative study included 41 patients with nonresolving central serous chorioretinopathy who exhibited subretinal fluid accumulation for more than 3 months. Of the 41 patients, 18 (18 eyes) received oral spironolactone treatment and 23 (23 eyes) received half-dose PDT. Treatment outcomes, including the central macular thickness, subretinal fluid height, subfoveal choroidal thickness, and best-corrected visual acuity, were measured at baseline and 1 and 3 months after treatment. RESULTS: There were no differences in baseline characteristics between the two groups. The central macular thickness and the subretinal fluid height significantly decreased at 1 and 3 months after treatment. The central macular thickness at 1 month was lesser in the PDT group than in the spironolactone group. The subfoveal choroidal thickness decreased at 1 and 3 months only in the PDT group, whereas best-corrected visual acuity showed a significant improvement at 3 months in both groups. CONCLUSION: Our results suggest that the short-term efficacy of oral spironolactone treatment for the management of nonresolving central serous chorioretinopathy is comparable with that of half-dose PDT, with an excellent safety profile. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | COMPARISON OF SHORT-TERM EFFICACY BETWEEN ORAL SPIRONOLACTONE TREATMENT AND PHOTODYNAMIC THERAPY FOR THE TREATMENT OF NONRESOLVING CENTRAL SEROUS CHORIORETINOPATHY | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Ophthalmology (안과학교실) | - |
dc.contributor.googleauthor | Lee, Ji Hwan | - |
dc.contributor.googleauthor | Lee, Sung Chul | - |
dc.contributor.googleauthor | Kim, Hyesun | - |
dc.contributor.googleauthor | Lee, Christopher Seungkyu | - |
dc.identifier.doi | 10.1097/IAE.0000000000001913 | - |
dc.contributor.localId | A02873 | - |
dc.contributor.localId | A02913 | - |
dc.contributor.localId | A03222 | - |
dc.relation.journalcode | J02621 | - |
dc.identifier.eissn | 1539-2864 | - |
dc.identifier.pmid | 29095358 | - |
dc.identifier.url | https://oce.ovid.com/article/00006982-201901000-00014/HTML | - |
dc.contributor.alternativeName | Lee, Sung Chul | - |
dc.contributor.affiliatedAuthor | 이성철 | - |
dc.contributor.affiliatedAuthor | 이승규 | - |
dc.contributor.affiliatedAuthor | 이지환 | - |
dc.citation.volume | 39 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 127 | - |
dc.citation.endPage | 133 | - |
dc.identifier.bibliographicCitation | RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES, Vol.39(1) : 127-133, 2019 | - |
dc.identifier.rimsid | 63006 | - |
dc.type.rims | ART | - |
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