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Quality of life, patient satisfaction, and disease burden in patients with gastroesophageal reflux disease with or without laryngopharyngeal reflux symptoms

Authors
 Eun Jeong Gong  ;  Kee Don Choi  ;  Hye‐Kyung Jung  ;  Young Hoon Youn  ;  Byung‐Hoon Min  ;  Kyung Ho Song  ;  Kyu Chan Huh 
Citation
 JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, Vol.32(7) : 1336-1340, 2017 
Journal Title
 JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY 
ISSN
 0815-9319 
Issue Date
2017
MeSH
Absenteeism ; Adult ; Asian Continental Ancestry Group ; Cost of Illness* ; Female ; Gastroesophageal Reflux/physiopathology* ; Gastroesophageal Reflux/psychology* ; Humans ; Linear Models ; Male ; Middle Aged ; Patient Satisfaction* ; Quality of Life* ; Severity of Illness Index ; Surveys and Questionnaires ; Work Performance
Keywords
gastroesophageal reflux disease ; laryngopharyngeal reflux ; quality of life
Abstract
BACKGROUND AND AIM: Patients with gastroesophageal reflux disease (GERD) have decreased health-related quality of life (HRQL). The quality of life in patients with laryngopharyngeal reflux (LPR) symptoms is also significantly impaired. However, the impact of LPR symptoms on HRQL in GERD patients has not been studied. METHODS: A nationwide, random-sample, and face-to-face survey of 300 Korean patients with GERD was conducted from January to March 2013. Gastroesophageal reflux symptoms were assessed using the Rome III questionnaire, LPR symptoms using the reflux symptom index, and HRQL using the EuroQol five dimensions (EQ-5D) questionnaire. A structured questionnaire on patient satisfaction, sickness-related absences, and health-related work productivity was also used. RESULTS: Among the 300 patients with GERD, 150 had LPR symptoms. The mean EQ-5D index was lower in patients with GERD and LPR symptoms than in those without LPR (0.88 vs 0.91, P = 0.002). A linear regression model showed that the severity of LPR symptoms was related to decreased HRQL and was independent of age, marital status, body mass index, or household income. The overall satisfaction rate regarding treatment was lower in patients with GERD and LPR (40.0% vs 69.1%, P = 0.040). GERD patients with LPR symptoms reported greater sickness-related absent hours per week (0.36 vs 0.02 h, P = 0.016) and greater percentages of overall work impairment than those without LPR (31.1% vs 20.8%, P < 0.001). CONCLUSIONS: Gastroesophageal reflux disease patients with LPR symptoms have a poorer HRQL, a lower satisfaction rate, and a greater disease burden than those without LPR.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1111/jgh.13716
DOI
10.1111/jgh.13716
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Song, Si Young(송시영) ORCID logo https://orcid.org/0000-0002-1417-4314
Youn, Young Hoon(윤영훈) ORCID logo https://orcid.org/0000-0002-0071-229X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/168002
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