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Factors associated with continuing medical therapy after transurethral resection of prostate

Authors
 Hyun Ho Han  ;  Woo Jin Ko  ;  Tag Keun Yoo  ;  Tae Hee Oh  ;  Duk Yoon Kim  ;  Dong Deuk Kwon  ;  Seok-Soo Byun  ;  Sun Il Kim  ;  Tae Young Jung 
Citation
 UROLOGY, Vol.84(3) : 675-680, 2014 
Journal Title
 UROLOGY 
ISSN
 0090-4295 
Issue Date
2014
Abstract
OBJECTIVE: To report the clinical characteristics of patients who have persistent lower urinary tract symptoms (LUTS) after surgery for benign prostatic hyperplasia (BPH) and continue their medical therapy postoperatively. MATERIALS AND METHODS: We retrospectively studied 372 patients who underwent transurethral resection of prostate for LUTS/BPH in 8 institutions to determine the differences between patients who continued LUTS/BPH medications for >3 months after surgery and those who did not. Preoperative, intraoperative, and postoperative clinical parameters were assessed. The Student t test and chi square test were used to compare each parameter between patient groups. Multivariate logistic regression analysis was performed to identify risk factors for persistent LUTS and continuing medical therapy after surgery. RESULTS: There were 205 patients (55.1%) who continued their LUTS/BPH medications for >3 months postoperatively. They reported poorer International Prostate Symptom Scores and uroflowmetry results after surgery. Multivariate analysis showed that age >70 years (odds ratio [OR], 2.474; P = .001), history of diabetes (OR, 1.949; P = .040), history of cerebrovascular accident (OR, 5.932; P = .001), any previous LUTS/BPH medication use (OR, 5.384; P = <0.001), and previous antimuscarinic drug use (OR, 2.962; P = .016) were significantly associated with symptom persistency and continuing medical therapy. CONCLUSION: Many patients have persistent voiding dysfunction after surgical treatment for LUTS/BPH. Older age, history of diabetes, history of cerebrovascular accidents, and preoperative antimuscarinic drug uses are possible risk factors.
Full Text
https://www.sciencedirect.com/science/article/pii/S0090429514003963
DOI
10.1016/j.urology.2014.04.027
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers
Yonsei Authors
Ko, Woo Jin(고우진)
Han, Hyun Ho(한현호) ORCID logo https://orcid.org/0000-0002-6268-0860
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167901
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