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혈우병관절건강점수와 페터슨점수로 평가한 혈우병 환자의 관절 건강

Other Titles
 Joint Health Status in Hemophilia Patients Using Hemophilia Joing Health Score and Pettersson Score 
Authors
 노윤영  ;  최영하  ;  박미나  ;  한정화  ;  김선희  ;  신윤정  ;  한승민  ;  이희영  ;  박정민  ;  홍준표  ;  유철주  ;  한정우 
Citation
 Clinical Pediatric Hematology-Oncology, Vol.25(2) : 108-115, 2018 
Journal Title
 Clinical Pediatric Hematology-Oncology 
ISSN
 2233-5250 
Issue Date
2018
Keywords
Hemophilia ; Arthropathies ; Level of health ; Patient outcome assessment
Abstract
Background: Comprehensive clinical and radiologic follow-up is needed to preserve joint functions and quality of life in hemophilia using clinimetric tools such as Hemophilia joint health score (HJHS) or Pettersson score (PS). We investigated the joint health status evaluated using the tools in Korean hemophilia patients. Methods: We reviewed retrospectively medical records to collect clinical parameters, HJHS and PS, who were followed up in Severance Hospital, Seoul, Korea. The correlation between HJHS and PS, and the effect of the prophylaxis for hemophilia on the outcomes measured with the scores were evaluated. The prophylaxis proportion (PP) was calculated as the proportion of prophylaxis duration to each patient’s life time. Results: Total of 28 patients with severe hemophilia were enrolled. Twelve patients (42.8%) were less than 20 years old. Total of 23 patients had experienced prophylaxis during their lives, and median PP was 39.7%. There was significant correlation between HJHS and PS (P<0.001). Each score was positively correlated with patient’s age (P<0.001). PP was negatively correlated with either HJHS or PS (P<0.001, respectively). There was significant correlation between either HJHS or PS and the PP in the group of patients <20 years old, but there was no correlation in the group of >20 years old. Conclusion: HJHS and PS were positively correlated. Each score increased as the patient’s age increased. The prophylaxis had protective effect on joint health. The prospective evaluation of HJHS and PS will be needed to prove the effect of proper management on the joint health status.
Files in This Item:
T201805680.pdf Download
DOI
10.15264/cpho.2018.25.2.108
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
유철주(Lyu, Chuhl Joo) ORCID logo https://orcid.org/0000-0001-7124-7818
한승민(Hahn, Seung Min) ORCID logo https://orcid.org/0000-0001-9832-6380
한정우(Han, Jung Woo) ORCID logo https://orcid.org/0000-0001-8936-1205
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167612
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