Cited 25 times in
Short-Term Outcome of Ischemic Stroke Patients With Systemic Malignancy
DC Field | Value | Language |
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dc.contributor.author | 김영대 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 유준상 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 허지회 | - |
dc.date.accessioned | 2019-03-15T02:27:55Z | - |
dc.date.available | 2019-03-15T02:27:55Z | - |
dc.date.issued | 2019 | - |
dc.identifier.issn | 0039-2499 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/167495 | - |
dc.description.abstract | Background and Purpose- Recent guidelines have suggested the potential benefit of intravenous thrombolysis in stroke patients with systemic malignancy who have a reasonable life expectancy of >6 months. However, it is difficult to determine which patients with cancer will have a life expectancy of >6 months. Therefore, we identified the factors associated with 6-month mortality in patients with acute ischemic stroke and systemic malignancy. Methods- Consecutive stroke patients with systemic malignancy were retrospectively analyzed. We classified the patients into 3 groups: the nonactive cancer, active nonmetastatic cancer, and metastatic cancer groups. We compared the baseline characteristics and 6-month survival rates. Results- Of the 468 ischemic stroke patients with systemic malignancy during an 8-year period, 223 patients had nonactive cancer, 105 patients had active nonmetastatic cancer, and 140 patients had metastasis. During the 6-month follow-up, 122 patients (26.1%) died (nonactive cancer group [7.2%, 16/223], active nonmetastatic cancer group [11.4%, 12/105], and metastatic cancer group [67.1%, 94/140]). Multivariate Cox regression analysis revealed that the presence of metastasis (hazard ratio, 4.527; 95% CI, 2.175-9.422) was independently associated with 6-month mortality. However, the active nonmetastatic cancer group exhibited similar 6-month mortality to the nonactive cancer group (hazard ratio, 0.711; 95% CI, 0.282-1.795). Gastric/esophageal cancer and pancreatic cancer were also independently associated with 6-month mortality (hazard ratio, 2.068 and 2.389, respectively). Conclusions- In stroke patients with active cancer, the presence of metastasis and the cancer type were crucial factors associated with 6-month mortality. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Lippincott Williams & Wilkins | - |
dc.relation.isPartOf | STROKE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Short-Term Outcome of Ischemic Stroke Patients With Systemic Malignancy | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Neurology (신경과학교실) | - |
dc.contributor.googleauthor | Joonsang Yoo | - |
dc.contributor.googleauthor | Hyo Suk Nam | - |
dc.contributor.googleauthor | Young Dae Kim | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.identifier.doi | 10.1161/STROKEAHA.118.023044 | - |
dc.contributor.localId | A00702 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A02513 | - |
dc.contributor.localId | A03312 | - |
dc.contributor.localId | A04369 | - |
dc.relation.journalcode | J02690 | - |
dc.identifier.eissn | 1524-4628 | - |
dc.identifier.pmid | 30626288 | - |
dc.identifier.url | https://www.ahajournals.org/doi/full/10.1161/STROKEAHA.118.023044 | - |
dc.subject.keyword | cancer | - |
dc.subject.keyword | follow-up studies | - |
dc.subject.keyword | mortality | - |
dc.subject.keyword | stroke | - |
dc.contributor.alternativeName | Kim, Young Dae | - |
dc.contributor.affiliatedAuthor | 김영대 | - |
dc.contributor.affiliatedAuthor | 남효석 | - |
dc.contributor.affiliatedAuthor | 유준상 | - |
dc.contributor.affiliatedAuthor | 이혜선 | - |
dc.contributor.affiliatedAuthor | 허지회 | - |
dc.citation.volume | 50 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 507 | - |
dc.citation.endPage | 511 | - |
dc.identifier.bibliographicCitation | STROKE, Vol.50(2) : 507-511, 2019 | - |
dc.identifier.rimsid | 40991 | - |
dc.type.rims | ART | - |
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