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Prescription Patterns and Burden of Pediatric Asthma in Korea

Authors
 In Suk Sol  ;  Yoon Hee Kim  ;  Soo Yeon Kim  ;  Sun Ha Choi  ;  Jong Deok Kim  ;  Bo Ok Kim  ;  Ji Eun Moon  ;  Kyung Won Kim  ;  Myung Hyun Sohn 
Citation
 Allergy Asthma & Immunology Research, Vol.11(2) : 280-290, 2019 
Journal Title
 Allergy Asthma & Immunology Research 
ISSN
 2092-7355 
Issue Date
2019
Keywords
Asthma ; child ; illness burden ; insurance claims analysis ; prescription ; prevalence
Abstract
PURPOSE: This study aimed to estimate the prevalence, prescription pattern and burden of pediatric asthma in Korea by analyzing the National Health Insurance (NHI) claims data. METHODS: We retrospectively analyzed the insurance claim records from the Korean NHI claims database from January 2010 to December 2014. Asthmatic patients were defined as children younger than 18 years, with appropriate 10th Revision of the International Classification of Diseases codes (J45 or J46) and a prescription for 1 or more asthma maintenance medications at the same date. Hospitalization and emergency department visits for asthma were defined as use of short-acting beta₂-agonists during hospital visits among asthmatic patients. RESULTS: There were 1,172,807 asthmatic children in 2010, which increased steadily to 1,590,228 in 2014 in Korea. The prevalence showed an increasing trend annually for all ages. The mean prevalence by age in those older than 2 years decreased during the study period (from 39.4% in the 2-3 year age group to 2.6% in the 15-18 year age group). In an outpatient prescription, leukotriene receptor antagonists were the most commonly prescribed medication for all ages. Patients older than 6 years for whom inhaled corticosteroids were prescribed comprised less than 15% of asthmatic patients. The total direct medical cost for asthma between 2010 and 2014 ranged from $376 to $483 million. Asthma-related medical cost per person reached its peak in $366 in 2011 and decreased to $275 in 2014. CONCLUSIONS: The prevalence of pediatric asthma increased annually and decreased with age. Individual cost of asthma showed a decreasing trend in Korean children.
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DOI
10.4168/aair.2019.11.2.280
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
김경원(Kim, Kyung Won) ORCID logo https://orcid.org/0000-0003-4529-6135
김수연(Kim, Soo Yeon) ORCID logo https://orcid.org/0000-0003-4965-6193
김윤희(Kim, Yoon Hee) ORCID logo https://orcid.org/0000-0002-2149-8501
김종덕(Kim, Jong Deok)
설인숙(Sol, In Suk) ORCID logo https://orcid.org/0000-0003-2470-9682
손명현(Sohn, Myung Hyun) ORCID logo https://orcid.org/0000-0002-2478-487X
최선하(Choi, Sun Ha)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167465
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