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약제유발 면역용혈성 빈혈의 검사실 규명

Other Titles
 Laboratory Workup of Drug-Induced Immune Hemolytic Anemia 
Authors
 나현진  ;  김현옥 
Citation
 Korean Journal of Blood Transfusion (대한수혈학회지), Vol.29(1) : 18-32, 2018 
Journal Title
 Korean Journal of Blood Transfusion (대한수혈학회지) 
ISSN
 1226-9336 
Issue Date
2018
Keywords
Drug-induced immune hemolytic anemia ; Role of laboratory physician ; Stepwise approach ; Prompt diagnosis ; Mechanisms of DIIHA
Abstract
Drug-induced immune hemolytic anemia (DIIHA) is rare condition that is often very difficult to diagnose. For proper diagnosis of DIIHA, careful interpretation of laboratory findings as well as correlation between those findings with the patient’s history is important. Therefore, the role of the laboratory physician is critical. DIIHA can be diagnosed using a stepwise approach, from suspicion of hemolytic anemia in the patient to confirmation of serologic tests. Prompt diagnosis is necessary since an essential part of DIIHA treatment is to cease drug administration, and many cases of hemolysis can be improved without further intervention. Furthermore, distinction between the mechanisms of DIIHA is important, as clinical manifestation, treatment options, and prognosis of the disease can differ according to the main mechanism involved in the process of hemolysis.
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DOI
10.17945/kjbt.2018.29.1.18
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
김현옥(Kim, Hyun Ok) ORCID logo https://orcid.org/0000-0002-4964-1963
나현진(Nah, Hyunjin)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167241
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