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The Potential Use of a Ketogenic Diet in Pancreatobiliary Cancer Patients After Pancreatectomy

Authors
 JU HYE OK  ;  HOSUN LEE  ;  HAE-YUN CHUNG  ;  SUNG HWAN LEE  ;  EUN JEONG CHOI  ;  CHANG MOO KANG  ;  SONG MI LEE 
Citation
 ANTICANCER RESEARCH, Vol.38(11) : 6519-6527, 2018 
Journal Title
 ANTICANCER RESEARCH 
ISSN
 0250-7005 
Issue Date
2018
MeSH
Adult ; Aged ; Biliary Tract Neoplasms/diet therapy* ; Biliary Tract Neoplasms/surgery* ; Chemotherapy, Adjuvant ; Diet, Ketogenic/methods* ; Energy Metabolism ; Female ; Hospitalization ; Humans ; Male ; Middle Aged ; Nutritional Status ; Pancreatectomy ; Pancreatic Neoplasms/diet therapy* ; Pancreatic Neoplasms/surgery* ; Patient Compliance ; Patient Satisfaction ; Prospective Studies ; Treatment Outcome
Keywords
Pancreatic cancer ; adjuvant anti-cancer therapy ; ketogenic diet ; pancreatectomy
Abstract
BACKGROUND/AIM: High-carbohydrate diets are generally provided to post-pancreatectomy cancer patients. Low energy density of this diet may obstruct proper energy intake and recovery. This study aimed to assess the effects of high-fat, high-energy ketogenic diet (KD) in these patients. PATIENTS AND METHODS: After pancreatectomy, 9 patients were provided with general diet (GD) while 10 were served KD. Meal compliance, energy intake rate, meal satisfaction and presence of complications were monitored throughout hospital stay. Data on nutritional status, serum lipids and body composition were collected and compared between groups. RESULTS: Meal compliance, energy intake rate and meal satisfaction score were higher in KD. There were no differences in complications, nutritional status and serum lipids. The decrease in body cell mass (BCM) was greater in GD. CONCLUSION: Post-pancreatectomy cancer patients who consumed KD had a higher energy intake and BCM. These results suggest the potential use of KD as an adjuvant anti-cancer therapy.
Full Text
http://ar.iiarjournals.org/content/38/11/6519.long
DOI
10.21873/anticanres.13017
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Chang Moo(강창무) ORCID logo https://orcid.org/0000-0002-5382-4658
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/167107
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