Cited 0 times in
Combined effects of a chemically cross-linked porcine collagen membrane and highly soluble biphasic calcium phosphate on localized bone regeneration
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김유경 | - |
dc.contributor.author | 이중석 | - |
dc.contributor.author | 정의원 | - |
dc.contributor.author | 차재국 | - |
dc.contributor.author | 최성호 | - |
dc.date.accessioned | 2019-01-15T17:00:19Z | - |
dc.date.available | 2019-01-15T17:00:19Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0376-4672 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166755 | - |
dc.description.abstract | Objectives: Aim of this study was to evaluate bone regenerative efficacy of a chemically cross-linked porcine collagen membrane (CM) when used in combination with highly soluble biphasic calcium phosphate (BCP). Materials and methods: Physiochemical properties of the experimental collagen membrane were analyzed. Four circumferential defects with diameter of 8 mm were created in each calvarium of New Zealand white rabbits (n = 10). Defects were randomly allocated to one of following 4 groups: 1) BCP-CM (BCP (20% hydroxyapatite/80% β-tricalcium phosphate) covered with the prepared collagen membrane), 2) BCP (only BCP used), 3) CM (only the prepared collagen membrane used), and 4) C (control; only blood clot). After 2 weeks (n = 5) and 8 weeks (n = 5), histologic and histomorphometric analyses were performed. Results: The experimental collagen membrane exhibited dense and compact structure, relatively high tensile strength and lower degradability. Histologic analyses revealed that new bone increased rapidly at 2 weeks, while defect was preserved at 8 weeks. Histomorphometric analyses revealed that the new bone areas increased in the BCP-grafted groups over 8 weeks, with BCP-CM exhibiting greater total augmented area than that of BCP group both at 2 weeks (27.12±3.99 versus 21.97±2.27 ㎟) and 8 weeks (25.75±1.82 versus 22.48±1.10 ㎟) (P < 0.05). Conclusions: The experimental collagen membrane successfully preserved localized defect for 8 weeks despite early rapid resorption of BCP. Within the study limitations, combined use of the chemically cross-linked porcine collagen membrane and highly soluble BCP aided localized bone regeneration. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | Korean | - |
dc.publisher | 대한치과의사협회 | - |
dc.relation.isPartOf | Journal of the Korean Dental Association (대한치과의사협회지) | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Biodegradation | - |
dc.subject.MESH | Biphasic calcium phosphate | - |
dc.subject.MESH | Bone regeneration | - |
dc.subject.MESH | Bone substitute | - |
dc.subject.MESH | Collagen membrane | - |
dc.title | Combined effects of a chemically cross-linked porcine collagen membrane and highly soluble biphasic calcium phosphate on localized bone regeneration | - |
dc.type | Article | - |
dc.contributor.college | College of Dentistry (치과대학) | - |
dc.contributor.department | Dept. of Periodontics (치주과학교실) | - |
dc.contributor.googleauthor | You-Kyoung Kim | - |
dc.contributor.googleauthor | Yin-Zhe An | - |
dc.contributor.googleauthor | Jae-Kook Cha | - |
dc.contributor.googleauthor | Jung-Seok Lee | - |
dc.contributor.googleauthor | Ui-Won Jung | - |
dc.contributor.googleauthor | Seong-Ho Choi | - |
dc.contributor.localId | A04729 | - |
dc.contributor.localId | A03185 | - |
dc.contributor.localId | A03692 | - |
dc.contributor.localId | A04004 | - |
dc.contributor.localId | A04081 | - |
dc.relation.journalcode | J01820 | - |
dc.contributor.alternativeName | Kim, You-Kyoung | - |
dc.contributor.affiliatedAuthor | 김유경 | - |
dc.contributor.affiliatedAuthor | 이중석 | - |
dc.contributor.affiliatedAuthor | 정의원 | - |
dc.contributor.affiliatedAuthor | 차재국 | - |
dc.contributor.affiliatedAuthor | 최성호 | - |
dc.citation.volume | 56 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 667 | - |
dc.citation.endPage | 685 | - |
dc.identifier.bibliographicCitation | Journal of the Korean Dental Association (대한치과의사협회지), Vol.56(12) : 667-685, 2018 | - |
dc.identifier.rimsid | 58023 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.