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소아 마이코플라스마 폐렴에서 Chorus Mycoplasma pneumoniae IgM Index와 임상양상과의 연관성

Other Titles
 Relationship between Chorus Mycoplasma pneumoniae IgM Index and Clinical Manifestations in Pediatric Mycoplasma Pneumonia 
Authors
 오승환 
Citation
 Newest Medical Journal (최신의학), Vol.56(2) : 51-61, 2013 
Journal Title
 Newest Medical Journal (최신의학) 
ISSN
 0529-3804 
Issue Date
2013
Keywords
anti-Mycoplasma pneumoniae IgM index ; Children ; Mycoplasma pneumoniae pneumonia
Abstract
Purpose: Mycoplasma pneumoniae (MP) has become a very important pathogen in childhood community-acquired pneumonia and usually detected with a immunological method. There had been a few studies for relationship of its antibody titer with the clinical features, so this study has been done to know it. Methods: I collected the informations of MP pneumonia patients who had been admitted and diagnosed with Chorus anti-Mycoplasma Pneumoniae IgM index method at the Department of Pediatrics, Yongin Severance Hospital, Yongin, Korea from September 2010 to December 2011. I divided the patients to group A(>5.0) and group B (≤5.0 and ≥1.1) by index value and compared them. Results: There were 99 cases for group A(55 boys and 44 girls) and 170 cases(83 boys and 87 girls) for group B. The mean ages for group A and group B were 4.4±3.0 years old and 5.0±3.0 years old respectively(P=0.167). There was no difference for sex ratio(P=0.287). The frequent clinical findings for group A and B were cough(100.0% versus 96.5%, P=0.088), sputum(96.0% versus 90.6%, P=0.105), fever(89.9% versus 90.0%, P=0.979), and rale(71.8% versus 61.2%, P=0.080). Chest radiographic infiltration had been found in 94 cases(95.0%) of group A and 154 cases(90.6%) of group B(P=0.198). Group A had longer durations of pre-admission fever(3.7±3.5 days versus 2.8±2.2 days, P=0.007), cough(6.7±5.3 days versus 5.2±5.5 days, P=0.030), sputum(6.7±5.6 days versus 4.7±5.4 days, P=0.014), more frequent vomiting(17.2% versus 8.8%, P=0.041), urinary ketone(10.1% versus 3.5%, P=0.028) and pyuria(18.2% versus 9.4%, P=0.038), more peripheral blood platelet counts (324,180.7 ± 96,279.3/μL versus 269,117.5±91,421.2/μL, P=0.00004), faster erythrocyte sedimentation rate (29.9±15.1 mm/hr versus 26.3±13.7 mm/hr, P=0.048) than group B. The admission durations were 4.2±1.5 days for group A and 4.2±1.4 days for group B(P=0.912). Conclusion: The Chorus anti-Mycoplasma pneumoniae IgM index titer is related with the initial clinical severity, but it does not predict the short-term prognosis. Continuous monitoring and study for it should be carried on to know its relevance to long-term prognosis.
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아청소년과학교실) > 1. Journal Papers
Yonsei Authors
Oh, Seung Hwan(오승환) ORCID logo https://orcid.org/0000-0003-0829-0711
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/166275
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