최근 10년간 용인지역 소아 마이코플라스마 폐렴의 발생 양상

Abstract

Purpose: Mycoplasma Pneumoniae(MP) is an important cause of community acquired pneumonia. The occurrence pattern of MP pneumonia should be helpful for its management, but it had not been studied in Korea since 2003. The purpose of this study is to know its recent features. Methods: I collected the patients numbers of community-acquired pneumonia and MP pneumonia patients who had been admitted and diagnosed by serologic methods at the Department of Pediatrics , Yongin Severance Hospital, Yongin, Korea from January 2002 to December 2011. I investigated and analyzed the MP pneumonia patients characteristics such as admission year , months, age, and sex. Results: There were 917 cases(19.4%) of MP pneumonia among 4726 cases of communityacquired pneumonia(CAP) children for 10 years. Its annual incidence in CAP was from 5.8 to 49.7%. There were three epidemics by incidence which were in 2002(21.5%), 2006 to 2007(30.3-40.5%), 2011(49.7%). The mean age of MP pneumonia cases was 4.3± 2.8 years old and 735 cases(80.1%) of them were younger than seven years old. Sex ratio was 1:1. The peak age was 2 years old. The patient proportion under three years old during epidemics was gradually increased from 2002(30.3%) to 2006(34.2%) and 2007(38.3%) but decreased in 2011(26.9%). The mean ages between recent two epidemics(2006 and 2007 versus 2011) were significantly different(4.3± 2.8 and 3.6± 2.4 versus 5.0± 3.2 years old, P=0.000008). The male to female ratio was different between epidemic and endemic period until 2006(2002 vs 2003, 2002 vs 2005, 2005 vs 2006, P<0.05). There were peak occurrences on April and December 2002, October 2006, November 2007, September 2011. Conclusion: Epidemic of MP pneumonia has four years interval and 1-2 year duration. It is frequently observed under seven years old. The tendency of increasing rate in very young patients is not continued. The epidemiological characteristics of them are not the same among each epidemic as well as endemic. Continuous monitoring for its occurrence should be carried on to know the up-to-date features.