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Design of Polymeric Culture Substrates to Promote Proangiogenic Potential of Stem Cells
DC Field | Value | Language |
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dc.contributor.author | 권병주 | - |
dc.contributor.author | 이신정 | - |
dc.contributor.author | 윤영섭 | - |
dc.contributor.author | 박종철 | - |
dc.contributor.author | 성학준 | - |
dc.date.accessioned | 2018-12-06T16:41:41Z | - |
dc.date.available | 2018-12-06T16:41:41Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1616-5187 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/166061 | - |
dc.description.abstract | Stem cells are a promising cell source for regenerative medicine due to their differentiation and self-renewal capacities. In the field of regenerative medicine and tissue engineering, a variety of biomedical technologies have been tested to improve proangiogenic activities of stem cells. However, their therapeutic effect is found to be limited in the clinic because of cell loss, senescence, and insufficient therapeutic activities. To address this type of issue, advanced techniques for biomaterial synthesis and fabrication have been approached to mimic proangiogenic microenvironment and to direct proangiogenic activities. This review highlights the types of polymers and design strategies that have been studied to promote proangiogenic activities of stem cells. In particular, scaffolds, hydrogels, and surface topographies, as well as insight into their underlying mechanisms to improve proangiogenic activities are the focuses. The strategy to promote angiogenic activities of hMSCs by controlling substrate repellency is introduced, and the future direction is proposed | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Wiley-VCH | - |
dc.relation.isPartOf | MACROMOLECULAR BIOSCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Design of Polymeric Culture Substrates to Promote Proangiogenic Potential of Stem Cells | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Medical Engineering (의학공학교실) | - |
dc.contributor.googleauthor | Byeong‐Ju Kwon | - |
dc.contributor.googleauthor | Xintong Wang | - |
dc.contributor.googleauthor | Mi‐Lan Kang | - |
dc.contributor.googleauthor | Jin You | - |
dc.contributor.googleauthor | Shin‐Jeong Lee | - |
dc.contributor.googleauthor | Won Shik Kim | - |
dc.contributor.googleauthor | Young‐sup Yoon | - |
dc.contributor.googleauthor | Jong‐Chul Park | - |
dc.contributor.googleauthor | Hak‐Joon Sung | - |
dc.identifier.doi | 10.1002/mabi.201700340 | - |
dc.contributor.localId | A00218 | - |
dc.contributor.localId | A05377 | - |
dc.contributor.localId | A02579 | - |
dc.contributor.localId | A01662 | - |
dc.contributor.localId | A01958 | - |
dc.relation.journalcode | J02176 | - |
dc.identifier.eissn | 1616-5195 | - |
dc.identifier.pmid | 29285899 | - |
dc.identifier.url | https://onlinelibrary.wiley.com/doi/full/10.1002/mabi.201700340 | - |
dc.contributor.alternativeName | Kwon, Byeong Ju | - |
dc.contributor.affiliatedAuthor | 권병주 | - |
dc.contributor.affiliatedAuthor | 이신정 | - |
dc.contributor.affiliatedAuthor | 윤영섭 | - |
dc.contributor.affiliatedAuthor | 박종철 | - |
dc.contributor.affiliatedAuthor | 성학준 | - |
dc.citation.volume | 18 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 1700340 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR BIOSCIENCE, Vol.18(2) : 1700340, 2018 | - |
dc.identifier.rimsid | 59289 | - |
dc.type.rims | ART | - |
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