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Oncogenic osteomalacia associated with mesenchymal tumour detected by indium-111 octreotide scintigraphy

Authors
 Yumie Rhee  ;  Jong Doo Lee  ;  Kyoo Ho Shin  ;  Hyun Chul Lee  ;  Kap Bum Huh  ;  Sung‐Kil Lim 
Citation
 Clinical Endocrinology, Vol.54(4) : 551-554, 2001 
Journal Title
 Clinical Endocrinology 
ISSN
 0300-0664 
Issue Date
2001
MeSH
Adult ; Arthroplasty, Replacement, Hip ; Biomarkers/blood ; Femoral Neoplasms/diagnostic imaging* ; Femoral Neoplasms/metabolism ; Femoral Neoplasms/surgery ; Humans ; Indium Radioisotopes*/metabolism ; Magnetic Resonance Imaging ; Male ; Mesenchymoma/diagnostic imaging* ; Mesenchymoma/metabolism ; Mesenchymoma/surgery ; Octreotide*/metabolism ; Osteomalacia/diagnostic imaging* ; Osteomalacia/metabolism ; Osteomalacia/surgery ; Phosphates/blood ; Radionuclide Imaging ; Receptors, Somatostatin/metabolism
Abstract
In a 40-year-old man who had suffered from vague and generalized bone pains for 7 years due to oncogenic osteomalacia, the causative tumour was finally detected by Indium-111 octreotide scintigraphy. Some characteristics of the tumour associated with oncogenic osteomalacia, such as its size, growth rate, location and origin, often make the diagnosis difficult. However, the recent discovery of somatostatin receptors in mesenchymal tumours, which are the most common cause of oncogenic osteomalacia, has raised the possibility of early detection of this devastating disorder. Here, we report that radiolabelled octreotide scintigraphy has a potential role as a diagnostic tool in oncogenic osteomalacia. However, the exact role of somatostatin receptors in tumours associated with oncogenic osteomalacia still remains elusive.
Full Text
https://onlinelibrary.wiley.com/doi/full/10.1046/j.1365-2265.2001.01056.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Rhee, Yumie(이유미) ORCID logo https://orcid.org/0000-0003-4227-5638
Lee, Jong Doo(이종두)
Lee, Hyun Chul(이현철)
Lim, Sung Kil(임승길)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/166025
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