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간세포암의 근치적 절제 후 간내 재발암의 위험 인자 분석

DC Field Value Language
dc.contributor.author김강미-
dc.contributor.author최기홍-
dc.contributor.author한대훈-
dc.contributor.author김동현-
dc.contributor.author강창무-
dc.contributor.author최진섭-
dc.contributor.author박준용-
dc.contributor.author김도영-
dc.contributor.author한광협-
dc.contributor.author전재윤-
dc.contributor.author박영년-
dc.contributor.author이우정-
dc.date.accessioned2018-12-03T16:55:31Z-
dc.date.available2018-12-03T16:55:31Z-
dc.date.issued2008-
dc.identifier.issn1738-6349-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165984-
dc.description.abstractPurpose: Intrahepatic recurrent HCC has been classified according to location, the time to recurrence and the pattern of presentation. The purpose of this study is to classify intrahepatic recurrent HCCs into subgroups that have relatively similar recurrent patterns and to identify the risk factors for each recurrent type. Methods: A total of 353 patients were retrospectively studied. Intrahepatic recurrent HCC was classified into nodular recurrence (<4 nodules; type I), multinodular-diffuse recurrence (≥4 nodules; type II) and infiltrative recurrence (type III). The cut-off time between early and late recurrence was chosen to be 12 months following hepatectomy. Results: Among the 134 patients with only intrahepatic recurrence, 94 were type I, 27 were type II and 13 were type III. The median survival time following the recurrence of types I, II and III were 55, 16 and 8 months, respectively. As determined by multivariate analysis, perioperative transfusion and indocyanine green retention at 15 minutes (ICG R 15 >10%) were the independent risk factors for type I; an ICG R 15>10%, microvessel invasion and intrahepatic metastasis were the independent risk factors for type II; an ICG R 15>10% and microscopic portal vein invasion were the independent risk factors for type III. Multivariate analysis revealed that the prognosis of patients with IHR was associated with the recurrent types, the time to recurrence and the serum albumin level at the initial presentation. Following multivariate analysis, an ICG R 15>10% and intrahepatic metastasis were the independent risk factors for early type I recurrence; perioperative transfusion and a higher grade of hepatitis activity were the independent risk factors for late type I recurrence. Conclusions: The recurrent types and the time to recurrence may help us to predict the cellular origin of intrahepatic recurrent HCC and the prognosis of the patients who suffer with intrahepatic recurrent HCC.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageKorean Journal of Hepato-Biliary-Pancreatic Surgery-
dc.publisherKorean Journal of Hepato-Biliary-Pancreatic Surgery-
dc.relation.isPartOfKorean Journal of Hepato-Biliary-Pancreatic Surgery-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.title간세포암의 근치적 절제 후 간내 재발암의 위험 인자 분석-
dc.title.alternativeThe Risk Factors for the Intrahepatic Recurrence of Hepatocellular Carcinoma after Curative Resection-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Surgery (외과학교실)-
dc.contributor.googleauthor김강미-
dc.contributor.googleauthor최기홍-
dc.contributor.googleauthor한대훈-
dc.contributor.googleauthor김동현-
dc.contributor.googleauthor강창무-
dc.contributor.googleauthor최진섭-
dc.contributor.googleauthor박준용-
dc.contributor.googleauthor김도영-
dc.contributor.googleauthor한광협-
dc.contributor.googleauthor전재윤-
dc.contributor.googleauthor박영년-
dc.contributor.googleauthor이우정-
dc.contributor.localIdA00286-
dc.contributor.localIdA04046-
dc.contributor.localIdA04046-
dc.contributor.localIdA04273-
dc.contributor.localIdA04273-
dc.contributor.localIdA00415-
dc.contributor.localIdA00415-
dc.contributor.localIdA00088-
dc.contributor.localIdA00088-
dc.contributor.localIdA04199-
dc.contributor.localIdA04199-
dc.contributor.localIdA01675-
dc.contributor.localIdA01675-
dc.contributor.localIdA00384-
dc.contributor.localIdA00384-
dc.contributor.localIdA04268-
dc.contributor.localIdA04268-
dc.contributor.localIdA03544-
dc.contributor.localIdA03544-
dc.contributor.localIdA01563-
dc.contributor.localIdA01563-
dc.contributor.localIdA02993-
dc.contributor.localIdA02993-
dc.contributor.localIdA05620-
dc.contributor.localIdA05620-
dc.relation.journalcodeJ02035-
dc.identifier.eissn2288-9213-
dc.subject.keywordHepatocellular carcinoma-
dc.subject.keywordcurative resection-
dc.subject.keywordintrahepatic recurrence-
dc.subject.keywordrisk factor-
dc.subject.keywordprognosis-
dc.contributor.alternativeNameKim, Gangmi-
dc.contributor.affiliatedAuthor김강미-
dc.contributor.affiliatedAuthor최기홍-
dc.contributor.affiliatedAuthor최기홍-
dc.contributor.affiliatedAuthor한대훈-
dc.contributor.affiliatedAuthor한대훈-
dc.contributor.affiliatedAuthor김동현-
dc.contributor.affiliatedAuthor김동현-
dc.contributor.affiliatedAuthor강창무-
dc.contributor.affiliatedAuthor강창무-
dc.contributor.affiliatedAuthor최진섭-
dc.contributor.affiliatedAuthor최진섭-
dc.contributor.affiliatedAuthor박준용-
dc.contributor.affiliatedAuthor박준용-
dc.contributor.affiliatedAuthor김도영-
dc.contributor.affiliatedAuthor김도영-
dc.contributor.affiliatedAuthor한광협-
dc.contributor.affiliatedAuthor한광협-
dc.contributor.affiliatedAuthor전재윤-
dc.contributor.affiliatedAuthor전재윤-
dc.contributor.affiliatedAuthor박영년-
dc.contributor.affiliatedAuthor박영년-
dc.contributor.affiliatedAuthor이우정-
dc.contributor.affiliatedAuthor이우정-
dc.contributor.affiliatedAuthor김지혜-
dc.contributor.affiliatedAuthor김지혜-
dc.citation.volume12-
dc.citation.number4-
dc.citation.startPage222-
dc.citation.endPage231-
dc.identifier.bibliographicCitationKorean Journal of Hepato-Biliary-Pancreatic Surgery, Vol.12(4) : 222-231, 2008-
dc.identifier.rimsid57865-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Dermatology (피부과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers

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