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Morphometry of the superior temporal plane in schizophrenia: relationship to clinical correlates

Authors
 Benedicto Crespo-Facorro  ;  Jae-Jin Kim  ;  Eran Chemerinski  ;  Vincent Magnotta  ;  Nancy C. Andreasen  ;  Peg Nopoulos 
Citation
 JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES, Vol.16(3) : 284-294, 2004 
Journal Title
 JOURNAL OF NEUROPSYCHIATRY AND CLINICAL NEUROSCIENCES 
ISSN
 0895-0172 
Issue Date
2004
MeSH
Adult ; Brain Mapping ; Case-Control Studies ; Demography ; Female ; Functional Laterality/physiology ; Humans ; Image Processing, Computer-Assisted/methods ; Magnetic Resonance Imaging/methods* ; Male ; Psychiatric Status Rating Scales ; Reproducibility of Results ; Schizophrenia/pathology* ; Temporal Lobe/pathology*
Abstract
A magnetic-resonance-imaging-based method of cortical parcellation was used to evaluate the morphology of the superior temporal plane and its subregions (Heschl's gyrus [HG], planum temporale [PT], and planum polare [PP]) in a group of 30 patients with schizophrenia versus a matched group of healthy subjects. Right HG volume was significantly reduced in patients compared with control subjects. Each subregion showed a unique set of structure/function relationships: reduced volumes of the HG were associated with greater duration of illness; reduced volumes of the PT were associated with positive symptoms; and in most contrast, elevated volumes of the PP were associated with cumulative neuroleptic exposure
DOI
10.1176/jnp.16.3.284
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Jin(김재진) ORCID logo https://orcid.org/0000-0002-1395-4562
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/165912
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