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조현병 환자에서 보상 및 손실의 연합 학습의 특징

Other Titles
 The Characteristics of Associative Learning of Reward Approach and Loss Aversion in Schizophrenia 
 Sunyoung Park  ;  Seok-Hyeong Kim  ;  Il Ho Park  ;  Jung-Hwan Kim  ;  Jae-Jin Kim  ;  Min-Seong Koo  ;  Jungeun Song 
 Korean Journal of Schizophrenia Research (대한조현병학회지), Vol.15(2) : 59-65, 2012 
Journal Title
 Korean Journal of Schizophrenia Research (대한조현병학회지) 
Issue Date
Schizophrenia ; Reinforcement ; Reward learning ; Negative symptoms ; Anhedonia
Objectives: Schizophrenia patients have deficits of prediction and learning related to dopaminergic dysfunction. It is hypothesized that there would be different characteristics in associative learning of reward approach and loss aversion between controls and patients. Methods: Participants were 23 healthy participants and 20 out-patients fulfilling criteria for schizophrenia according DSM-IV-TR. Using a monetary incentive contingency reversal task, successful learning rates, numbers of trials and errors till learning, numbers of trials of maintaining learning, response times were measured. Characteristics of learning were compared between controls and patients. Results: Physical anhedonia and PANSS negative symptom scores correlated with the number of trials while loss aversion was maintained. Overall correct response rates were decreased in patient group, particularly during reward approach learning. Patients required more trials and errors to learn reward approach than controls. There were no significant differences in learning performance and reaction times between groups during loss avoidance learning. Conclusion: These results support previous reports of deficits in reward-driven learning in schizophrenia. However, anhedonia and negative symptoms were associated with the preserved function of loss avoidance learning.
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Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Psychiatry (정신과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jae Jin(김재진) ORCID logo https://orcid.org/0000-0002-1395-4562
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