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Can radial bone mineral density predict spinal bone mineral density in patients with advanced Duchenne muscular dystrophy?

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dc.contributor.author강성웅-
dc.contributor.author김은영-
dc.contributor.author최원아-
dc.contributor.author조한얼-
dc.date.accessioned2018-11-16T16:59:26Z-
dc.date.available2018-11-16T16:59:26Z-
dc.date.issued2018-
dc.identifier.issn0025-7974-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165551-
dc.description.abstractIn advanced Duchenne muscular dystrophy (DMD), patients with high bone fracture risk due to osteoporosis, it is difficult to measure spinal bone mineral density (BMD) because of maintaining proper posture. This study began with the idea that if we diagnose and manage osteoporosis by predicting spinal BMD through easily testable radial BMD, we could prevent fracture and improve quality of life in DMD patients. In 61 DMD patients aged 20 years or older who were admitted to Gangnam Severance Hospital from April 2013 to May 2015, radial BMD and spinal BMD were measured to compare their Z-scores. In 45 patients, the z-score was less than -2.0 in spinal BMD defined as osteoporosis. And the optimal range of Z-score in the radius was -5.2 to -5.0 (sensitivity 78.9%, specificity 71.4%). Only through the radius BMD, spinal BMD can be predicted and we suggest appropriate times for treatments.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherLippincott Williams & Wilkins-
dc.relation.isPartOfMEDICINE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAbsorptiometry, Photon/statistics & numerical data*-
dc.subject.MESHAdult-
dc.subject.MESHBone Density*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMuscular Dystrophy, Duchenne/complications-
dc.subject.MESHMuscular Dystrophy, Duchenne/diagnostic imaging*-
dc.subject.MESHOsteoporosis/diagnostic imaging*-
dc.subject.MESHOsteoporosis/etiology-
dc.subject.MESHOsteoporotic Fractures/diagnostic imaging-
dc.subject.MESHOsteoporotic Fractures/etiology-
dc.subject.MESHPredictive Value of Tests-
dc.subject.MESHRadius/diagnostic imaging*-
dc.subject.MESHRetrospective Studies-
dc.subject.MESHRisk Assessment/methods-
dc.subject.MESHSensitivity and Specificity-
dc.subject.MESHSpine/diagnostic imaging*-
dc.subject.MESHYoung Adult-
dc.titleCan radial bone mineral density predict spinal bone mineral density in patients with advanced Duchenne muscular dystrophy?-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Rehabilitation Medicine (재활의학교실)-
dc.contributor.googleauthorEunyoung Kim-
dc.contributor.googleauthorHan Eol Cho-
dc.contributor.googleauthorJi Ho Jung-
dc.contributor.googleauthorJang Woo Lee-
dc.contributor.googleauthorWon Ah Choi-
dc.contributor.googleauthorSeong-Woong Kang-
dc.identifier.doi10.1097/MD.0000000000012303-
dc.contributor.localIdA00041-
dc.contributor.localIdA05462-
dc.contributor.localIdA04125-
dc.relation.journalcodeJ02214-
dc.identifier.eissn1536-5964-
dc.identifier.pmid30290594-
dc.subject.keywordbone mineral density-
dc.subject.keyworddual X-ray absorptiometry-
dc.subject.keywordDuchenne muscular dystrophy-
dc.subject.keywordosteoporosis-
dc.contributor.alternativeNameKang, Seong Woong-
dc.contributor.alternativeNameKim, Eun Young-
dc.contributor.alternativeNameChoi, Won Ah-
dc.contributor.affiliatedAuthor강성웅-
dc.contributor.affiliatedAuthor김은영-
dc.contributor.affiliatedAuthor최원아-
dc.citation.volume97-
dc.citation.number40-
dc.citation.startPagee12303-
dc.identifier.bibliographicCitationMEDICINE, Vol.97(40) : e12303, 2018-
dc.identifier.rimsid59185-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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