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Changes in Clinical Characteristics of Patients with an Initial Diagnosis of Prostate Cancer in Korea: 10-Year Trends Reported by a Tertiary Center

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dc.contributor.author이광석-
dc.contributor.author정병하-
dc.date.accessioned2018-11-16T16:58:42Z-
dc.date.available2018-11-16T16:58:42Z-
dc.date.issued2018-
dc.identifier.issn1011-8934-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165536-
dc.description.abstractBACKGROUND: The Korea Central Cancer Registry reported that incidence rates of prostate cancer have not increased continuously. We used recent trends in the incidence of prostate cancer to generate a preliminary report of the Korean population with prostate cancer. METHODS: Patients initially diagnosed with prostate cancer by prostate biopsy from 2006 to 2015 at our tertiary center were selected. All patients were categorized according to age (< 65, 65-75, > 75 years), time period (2006-2010 vs. 2011-2015), and risk classification. Patients with insufficient data were excluded from the analysis. RESULTS: Of 675 patients (median prostate-specific antigen [PSA], 9.09 ng/mL), those with a Gleason score (GS) of 6 (32.3%) comprised the largest proportion in our cohort. The proportion with a GS of 8 increased for those aged 65-75 years, despite the lack of increase in PSA. Treatment patterns changed for those with very low to low risk cancer. The overall survival (OS) rate and the cancer-specific survival (CSS) rate for all patients at 5 years were 87% and 90%, respectively. Patients with a low body mass index (BMI; ≤ 23 kg/m²) had worse median OS and CSS rates. CONCLUSION: Significant differences in risk classifications and initial treatments were found between 2006-2010 and 2011-2015. Although PSA did not change, the GS did change. Lower BMI (≤ 23 kg/m²) had worse effects on OS and CSS rates for Korean prostate cancer patients.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisher대한의학회(The Korean Academy of Medical Sciences)-
dc.relation.isPartOfJOURNAL OF KOREAN MEDICAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged-
dc.subject.MESHBody Mass Index-
dc.subject.MESHDisease-Free Survival-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHMultivariate Analysis-
dc.subject.MESHNeoplasm Grading-
dc.subject.MESHNeoplasm Staging-
dc.subject.MESHProportional Hazards Models-
dc.subject.MESHProstate-Specific Antigen/analysis-
dc.subject.MESHProstatic Neoplasms/diagnosis*-
dc.subject.MESHProstatic Neoplasms/mortality-
dc.subject.MESHProstatic Neoplasms/pathology-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHSurvival Rate-
dc.subject.MESHTertiary Care Centers-
dc.titleChanges in Clinical Characteristics of Patients with an Initial Diagnosis of Prostate Cancer in Korea: 10-Year Trends Reported by a Tertiary Center-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Urology (비뇨의학교실)-
dc.contributor.googleauthorJi Eun Heo-
dc.contributor.googleauthorHyun Kyu Ahn-
dc.contributor.googleauthorJinu Kim-
dc.contributor.googleauthorByung Ha Chung-
dc.contributor.googleauthorKwang Suk Lee-
dc.identifier.doi10.3346/jkms.2018.33.e42-
dc.contributor.localIdA02668-
dc.contributor.localIdA03607-
dc.relation.journalcodeJ01517-
dc.identifier.eissn1598-6357-
dc.identifier.pmid29349937-
dc.subject.keywordBiopsy-
dc.subject.keywordGleason Score-
dc.subject.keywordNeoplasms, Prostate-
dc.subject.keywordProstate-Specific Antigen-
dc.contributor.alternativeNameLee, Kwang Suk-
dc.contributor.alternativeNameChung, Byung Ha-
dc.contributor.affiliatedAuthor이광석-
dc.contributor.affiliatedAuthor정병하-
dc.citation.volume33-
dc.citation.number6-
dc.citation.startPagee42-
dc.identifier.bibliographicCitationJOURNAL OF KOREAN MEDICAL SCIENCE, Vol.33(6) : e42, 2018-
dc.identifier.rimsid59170-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Urology (비뇨의학교실) > 1. Journal Papers

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