Cited 4 times in
Changes in Clinical Characteristics of Patients with an Initial Diagnosis of Prostate Cancer in Korea: 10-Year Trends Reported by a Tertiary Center
DC Field | Value | Language |
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dc.contributor.author | 이광석 | - |
dc.contributor.author | 정병하 | - |
dc.date.accessioned | 2018-11-16T16:58:42Z | - |
dc.date.available | 2018-11-16T16:58:42Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 1011-8934 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165536 | - |
dc.description.abstract | BACKGROUND: The Korea Central Cancer Registry reported that incidence rates of prostate cancer have not increased continuously. We used recent trends in the incidence of prostate cancer to generate a preliminary report of the Korean population with prostate cancer. METHODS: Patients initially diagnosed with prostate cancer by prostate biopsy from 2006 to 2015 at our tertiary center were selected. All patients were categorized according to age (< 65, 65-75, > 75 years), time period (2006-2010 vs. 2011-2015), and risk classification. Patients with insufficient data were excluded from the analysis. RESULTS: Of 675 patients (median prostate-specific antigen [PSA], 9.09 ng/mL), those with a Gleason score (GS) of 6 (32.3%) comprised the largest proportion in our cohort. The proportion with a GS of 8 increased for those aged 65-75 years, despite the lack of increase in PSA. Treatment patterns changed for those with very low to low risk cancer. The overall survival (OS) rate and the cancer-specific survival (CSS) rate for all patients at 5 years were 87% and 90%, respectively. Patients with a low body mass index (BMI; ≤ 23 kg/m²) had worse median OS and CSS rates. CONCLUSION: Significant differences in risk classifications and initial treatments were found between 2006-2010 and 2011-2015. Although PSA did not change, the GS did change. Lower BMI (≤ 23 kg/m²) had worse effects on OS and CSS rates for Korean prostate cancer patients. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | 대한의학회(The Korean Academy of Medical Sciences) | - |
dc.relation.isPartOf | JOURNAL OF KOREAN MEDICAL SCIENCE | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Body Mass Index | - |
dc.subject.MESH | Disease-Free Survival | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Neoplasm Grading | - |
dc.subject.MESH | Neoplasm Staging | - |
dc.subject.MESH | Proportional Hazards Models | - |
dc.subject.MESH | Prostate-Specific Antigen/analysis | - |
dc.subject.MESH | Prostatic Neoplasms/diagnosis* | - |
dc.subject.MESH | Prostatic Neoplasms/mortality | - |
dc.subject.MESH | Prostatic Neoplasms/pathology | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Survival Rate | - |
dc.subject.MESH | Tertiary Care Centers | - |
dc.title | Changes in Clinical Characteristics of Patients with an Initial Diagnosis of Prostate Cancer in Korea: 10-Year Trends Reported by a Tertiary Center | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Urology (비뇨의학교실) | - |
dc.contributor.googleauthor | Ji Eun Heo | - |
dc.contributor.googleauthor | Hyun Kyu Ahn | - |
dc.contributor.googleauthor | Jinu Kim | - |
dc.contributor.googleauthor | Byung Ha Chung | - |
dc.contributor.googleauthor | Kwang Suk Lee | - |
dc.identifier.doi | 10.3346/jkms.2018.33.e42 | - |
dc.contributor.localId | A02668 | - |
dc.contributor.localId | A03607 | - |
dc.relation.journalcode | J01517 | - |
dc.identifier.eissn | 1598-6357 | - |
dc.identifier.pmid | 29349937 | - |
dc.subject.keyword | Biopsy | - |
dc.subject.keyword | Gleason Score | - |
dc.subject.keyword | Neoplasms, Prostate | - |
dc.subject.keyword | Prostate-Specific Antigen | - |
dc.contributor.alternativeName | Lee, Kwang Suk | - |
dc.contributor.alternativeName | Chung, Byung Ha | - |
dc.contributor.affiliatedAuthor | 이광석 | - |
dc.contributor.affiliatedAuthor | 정병하 | - |
dc.citation.volume | 33 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | e42 | - |
dc.identifier.bibliographicCitation | JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.33(6) : e42, 2018 | - |
dc.identifier.rimsid | 59170 | - |
dc.type.rims | ART | - |
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