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Early Clinical Experience with Sutureless Aortic Valve Replacement for Severe Aortic Stenosis

 Do Jung Kim  ;  Hyo-Hyun Kim  ;  Shin-Young Lee  ;  Sak Lee  ;  Byung-Chul Chang 
 Korean Journal of Thoracic and Cardiovascular Surgery, Vol.51(1) : 1-7, 2018 
Journal Title
 Korean Journal of Thoracic and Cardiovascular Surgery 
Issue Date
Aortic valve stenosis ; Bioprosthesis ; Heart valve prosthesis implantation
Background: Sutureless aortic valve replacement (SU-AVR) has been developed as an alternative surgical treatment for patients with symptomatic severe aortic stenosis (AS). The aim of this study was to evaluate the clinical outcomes of SU-AVR through an assessment of hemodynamic performance and safety. Methods: From December 2014 to June 2016, a total of 12 consecutive patients with severe AS underwent SU-AVR. The endpoints were overall survival and valve-related complications (paravalvular leakage, valve thrombosis, migration, endocarditis, and permanent pacemaker implantation). The mean follow-up duration was 18.1±8.6 months. Results: The mean age of the patients was 77.1±5.8 years and their mean Society of Thoracic Surgeons score was 9.2±17.7. The mean cardiopulmonary bypass and aortic cross-clamp times were 94.5±37.3 minutes and 54.9±12.5 minutes, respectively. Follow-up echocardiography showed good prosthesis function with low transvalvular pressure gradients (mean, 13.9±8.6 mm Hg and peak, 27.2±15.0 mm Hg) at a mean of 9.9±4.2 months. No cases of primary paravalvular leakage, valve thrombosis, migration, or endocarditis were reported. A new permanent pacemaker was implanted in 1 patient (8.3%). The 1-year overall survival rate was 83.3%±10.8%. Conclusion: Our initial experience with SU-AVR demonstrated excellent early clinical outcomes with good hemodynamic results. However, there was a high incidence of permanent pacemaker implantation compared to the rate for conventional AVR, which is a problem that should be solved.
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1. College of Medicine (의과대학) > Dept. of Thoracic and Cardiovascular Surgery (흉부외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Do Jung(김도정)
Kim, Hyohyun(김효현) ORCID logo https://orcid.org/0000-0002-1608-9674
Lee, Sak(이삭) ORCID logo https://orcid.org/0000-0001-6130-2342
Lee, Shin Young(이신영)
Chang, Byung Chul(장병철)
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