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Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis

DC Field Value Language
dc.contributor.author구남수-
dc.contributor.author김준명-
dc.contributor.author나성원-
dc.contributor.author송제은-
dc.contributor.author안진영-
dc.contributor.author정수진-
dc.contributor.author조성래-
dc.contributor.author최준용-
dc.date.accessioned2018-11-16T16:43:54Z-
dc.date.available2018-11-16T16:43:54Z-
dc.date.issued2018-
dc.identifier.issn0513-5796-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/165273-
dc.description.abstractPURPOSE: Severe sepsis is associated with functional disability among patients surviving an acute phase of infection. Efforts to improve functional impairment are important. We assessed the effects of early exercise rehabilitation on functional outcomes in patients with severe sepsis. MATERIALS AND METHODS: A prospective, single-center, case-control study was conducted between January 2013 and May 2014 at a tertiary care center in Korea. Patients with severe sepsis and septic shock were enrolled and randomized to receive standard sepsis treatment or intervention. Intervention involved early targeted physical rehabilitation with sepsis treatment during hospitalization. Participants were assessed at enrollment, hospital discharge, and 6 months after enrollment. Functional recovery was measured using the Modified Barthel Index (MBI), Functional Independence Measure (FIM), and Instrumental Activities of Daily Living (IADL). RESULTS: Forty participants (21 intervention patients) were included in an intention-to-treat analysis. There were no significant differences in baseline MBI, FIM, and IADL between groups. Intervention yielded greater improvement of MBI, FIM, and IADL in the intervention group at hospital discharge, but not significantly. Subgroup analysis of patients with APACHE II scores ≥10 showed significantly greater improvement of physical function at hospital discharge (MBI and FIM) in the intervention group, compared to the control group (55.13 vs. 31.75, p=0.048; 52.40 vs. 31.25, p=0.045). Intervention was significantly associated with improvement of MBI in multiple linear regression analysis (standardized coefficient 0.358, p=0.048). CONCLUSION: Early physical rehabilitation may improve functional recovery at hospital discharge, especially in patients with high initial severity scores.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.languageEnglish-
dc.publisherYonsei University-
dc.relation.isPartOfYONSEI MEDICAL JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHActivities of Daily Living-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCase-Control Studies-
dc.subject.MESHExercise Therapy*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOutcome Assessment (Health Care)*-
dc.subject.MESHPatient Discharge-
dc.subject.MESHProspective Studies-
dc.subject.MESHRecovery of Function*-
dc.subject.MESHRegression Analysis-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHSepsis/rehabilitation*-
dc.subject.MESHShock, Septic/rehabilitation*-
dc.titleEffects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학교실)-
dc.contributor.googleauthorJin Young Ahn-
dc.contributor.googleauthorJe Eun Song-
dc.contributor.googleauthorHea Won Ann-
dc.contributor.googleauthorYongduk Jeon-
dc.contributor.googleauthorMi Young Ahn-
dc.contributor.googleauthorIn Young Jung-
dc.contributor.googleauthorMoo Hyun Kim-
dc.contributor.googleauthorWooyoung Jeong-
dc.contributor.googleauthorSu Jin Jeong-
dc.contributor.googleauthorNam Su Ku-
dc.contributor.googleauthorJune Myung Kim-
dc.contributor.googleauthorSungwon Na-
dc.contributor.googleauthorSung-Rae Cho-
dc.contributor.googleauthorJun Yong Choi-
dc.identifier.doi10.3349/ymj.2018.59.7.843-
dc.contributor.localIdA00189-
dc.contributor.localIdA00953-
dc.contributor.localIdA01232-
dc.contributor.localIdA02059-
dc.contributor.localIdA02267-
dc.contributor.localIdA03638-
dc.contributor.localIdA03831-
dc.contributor.localIdA04191-
dc.relation.journalcodeJ02813-
dc.identifier.eissn1976-2437-
dc.identifier.pmid30091317-
dc.subject.keywordSepsis-
dc.subject.keywordexercise rehabilitation-
dc.subject.keywordfunctional outcome-
dc.subject.keywordfunctional recovery-
dc.subject.keywordseptic shock-
dc.contributor.alternativeNameKu, Nam Su-
dc.contributor.alternativeNameKim, June Myung-
dc.contributor.alternativeNameNa, Sung Won-
dc.contributor.alternativeNameSong, Je Eun-
dc.contributor.alternativeNameAhn, Jin Young-
dc.contributor.alternativeNameJeong, Su Jin-
dc.contributor.alternativeNameCho, Sung Rae-
dc.contributor.alternativeNameChoi, Jun Yong-
dc.contributor.affiliatedAuthor구남수-
dc.contributor.affiliatedAuthor김준명-
dc.contributor.affiliatedAuthor나성원-
dc.contributor.affiliatedAuthor송제은-
dc.contributor.affiliatedAuthor안진영-
dc.contributor.affiliatedAuthor정수진-
dc.contributor.affiliatedAuthor조성래-
dc.contributor.affiliatedAuthor최준용-
dc.citation.volume59-
dc.citation.number7-
dc.citation.startPage843-
dc.citation.endPage851-
dc.identifier.bibliographicCitationYONSEI MEDICAL JOURNAL, Vol.59(7) : 843-851, 2018-
dc.identifier.rimsid58687-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Rehabilitation Medicine (재활의학교실) > 1. Journal Papers

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