Cited 12 times in
Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis
DC Field | Value | Language |
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dc.contributor.author | 구남수 | - |
dc.contributor.author | 김준명 | - |
dc.contributor.author | 나성원 | - |
dc.contributor.author | 송제은 | - |
dc.contributor.author | 안진영 | - |
dc.contributor.author | 정수진 | - |
dc.contributor.author | 조성래 | - |
dc.contributor.author | 최준용 | - |
dc.date.accessioned | 2018-11-16T16:43:54Z | - |
dc.date.available | 2018-11-16T16:43:54Z | - |
dc.date.issued | 2018 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165273 | - |
dc.description.abstract | PURPOSE: Severe sepsis is associated with functional disability among patients surviving an acute phase of infection. Efforts to improve functional impairment are important. We assessed the effects of early exercise rehabilitation on functional outcomes in patients with severe sepsis. MATERIALS AND METHODS: A prospective, single-center, case-control study was conducted between January 2013 and May 2014 at a tertiary care center in Korea. Patients with severe sepsis and septic shock were enrolled and randomized to receive standard sepsis treatment or intervention. Intervention involved early targeted physical rehabilitation with sepsis treatment during hospitalization. Participants were assessed at enrollment, hospital discharge, and 6 months after enrollment. Functional recovery was measured using the Modified Barthel Index (MBI), Functional Independence Measure (FIM), and Instrumental Activities of Daily Living (IADL). RESULTS: Forty participants (21 intervention patients) were included in an intention-to-treat analysis. There were no significant differences in baseline MBI, FIM, and IADL between groups. Intervention yielded greater improvement of MBI, FIM, and IADL in the intervention group at hospital discharge, but not significantly. Subgroup analysis of patients with APACHE II scores ≥10 showed significantly greater improvement of physical function at hospital discharge (MBI and FIM) in the intervention group, compared to the control group (55.13 vs. 31.75, p=0.048; 52.40 vs. 31.25, p=0.045). Intervention was significantly associated with improvement of MBI in multiple linear regression analysis (standardized coefficient 0.358, p=0.048). CONCLUSION: Early physical rehabilitation may improve functional recovery at hospital discharge, especially in patients with high initial severity scores. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.language | English | - |
dc.publisher | Yonsei University | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Activities of Daily Living | - |
dc.subject.MESH | Adult | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Case-Control Studies | - |
dc.subject.MESH | Exercise Therapy* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Outcome Assessment (Health Care)* | - |
dc.subject.MESH | Patient Discharge | - |
dc.subject.MESH | Prospective Studies | - |
dc.subject.MESH | Recovery of Function* | - |
dc.subject.MESH | Regression Analysis | - |
dc.subject.MESH | Republic of Korea | - |
dc.subject.MESH | Sepsis/rehabilitation* | - |
dc.subject.MESH | Shock, Septic/rehabilitation* | - |
dc.title | Effects of Early Exercise Rehabilitation on Functional Recovery in Patients with Severe Sepsis | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Internal Medicine (내과학교실) | - |
dc.contributor.googleauthor | Jin Young Ahn | - |
dc.contributor.googleauthor | Je Eun Song | - |
dc.contributor.googleauthor | Hea Won Ann | - |
dc.contributor.googleauthor | Yongduk Jeon | - |
dc.contributor.googleauthor | Mi Young Ahn | - |
dc.contributor.googleauthor | In Young Jung | - |
dc.contributor.googleauthor | Moo Hyun Kim | - |
dc.contributor.googleauthor | Wooyoung Jeong | - |
dc.contributor.googleauthor | Su Jin Jeong | - |
dc.contributor.googleauthor | Nam Su Ku | - |
dc.contributor.googleauthor | June Myung Kim | - |
dc.contributor.googleauthor | Sungwon Na | - |
dc.contributor.googleauthor | Sung-Rae Cho | - |
dc.contributor.googleauthor | Jun Yong Choi | - |
dc.identifier.doi | 10.3349/ymj.2018.59.7.843 | - |
dc.contributor.localId | A00189 | - |
dc.contributor.localId | A00953 | - |
dc.contributor.localId | A01232 | - |
dc.contributor.localId | A02059 | - |
dc.contributor.localId | A02267 | - |
dc.contributor.localId | A03638 | - |
dc.contributor.localId | A03831 | - |
dc.contributor.localId | A04191 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 30091317 | - |
dc.subject.keyword | Sepsis | - |
dc.subject.keyword | exercise rehabilitation | - |
dc.subject.keyword | functional outcome | - |
dc.subject.keyword | functional recovery | - |
dc.subject.keyword | septic shock | - |
dc.contributor.alternativeName | Ku, Nam Su | - |
dc.contributor.alternativeName | Kim, June Myung | - |
dc.contributor.alternativeName | Na, Sung Won | - |
dc.contributor.alternativeName | Song, Je Eun | - |
dc.contributor.alternativeName | Ahn, Jin Young | - |
dc.contributor.alternativeName | Jeong, Su Jin | - |
dc.contributor.alternativeName | Cho, Sung Rae | - |
dc.contributor.alternativeName | Choi, Jun Yong | - |
dc.contributor.affiliatedAuthor | 구남수 | - |
dc.contributor.affiliatedAuthor | 김준명 | - |
dc.contributor.affiliatedAuthor | 나성원 | - |
dc.contributor.affiliatedAuthor | 송제은 | - |
dc.contributor.affiliatedAuthor | 안진영 | - |
dc.contributor.affiliatedAuthor | 정수진 | - |
dc.contributor.affiliatedAuthor | 조성래 | - |
dc.contributor.affiliatedAuthor | 최준용 | - |
dc.citation.volume | 59 | - |
dc.citation.number | 7 | - |
dc.citation.startPage | 843 | - |
dc.citation.endPage | 851 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.59(7) : 843-851, 2018 | - |
dc.identifier.rimsid | 58687 | - |
dc.type.rims | ART | - |
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