Cited 5 times in
Differential cytokine responses of murine macrophage J774A.1 cells to stainless steel coated with and without hydroxyapatite
DC Field | Value | Language |
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dc.contributor.author | 박종철 | - |
dc.contributor.author | 이미희 | - |
dc.date.accessioned | 2018-11-05T16:40:01Z | - |
dc.date.available | 2018-11-05T16:40:01Z | - |
dc.date.issued | 2007 | - |
dc.identifier.issn | 0257-8972 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/165021 | - |
dc.description.abstract | Identification of cytokines secreted by macrophages and assessment of macrophage function in response to biomaterials is an important aspect of the host response to biomaterials. In the present study, differential cytokine responses of murine macrophage J774A.1 cells to stainless steel (SS) coated with and without hydroxyapatite (HA) were investigated. HA-coated SS was prepared through the deposition of thin (1 μm thick) calcium phosphate film by electron beam evaporation. SEM micrographs show that the surface of HA-coated SS was smoother than that of SS. Cell growth of J774A.1 macrophages onto HA-coated was about 1.5 times better than that onto intact SS. Reverse transcription-polymerase chain reaction analysis revealed that the mRNA of cytokines, such as tumor necrosis factor-α, transforming growth factor-β and granulocyte macrophage colony stimulating factor, was relatively less expressed in J774A.1 macrophages grown onto HA-coated SS. These results suggest that HA coatings may influence the expression of inflammatory cytokine in macrophages and improve the surface properties of metallic materials. | - |
dc.description.statementOfResponsibility | restriction | - |
dc.language | English | - |
dc.publisher | Elsevier Sequoia | - |
dc.relation.isPartOf | SURFACE & COATINGS TECHNOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Differential cytokine responses of murine macrophage J774A.1 cells to stainless steel coated with and without hydroxyapatite | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Medical Engineering (의학공학교실) | - |
dc.contributor.googleauthor | Mi Hee Lee | - |
dc.contributor.googleauthor | Dong-Wook Han | - |
dc.contributor.googleauthor | Hyun Sook Baek | - |
dc.contributor.googleauthor | Hye Ryun Lim | - |
dc.contributor.googleauthor | In-Seop Lee c, Kwon-Yong Lee d, Kyung Tae Kim e, Seung Jin Lee f, Jong-Chul Park | - |
dc.identifier.doi | 10.1016/j.surfcoat.2006.07.064 | - |
dc.contributor.localId | A01662 | - |
dc.contributor.localId | A02777 | - |
dc.relation.journalcode | J02698 | - |
dc.identifier.eissn | 1879-3347 | - |
dc.identifier.url | https://www.sciencedirect.com/science/article/pii/S0257897206006293 | - |
dc.subject.keyword | Cytokine | - |
dc.subject.keyword | Macrophage | - |
dc.subject.keyword | Biomaterials | - |
dc.subject.keyword | Stainless steel | - |
dc.subject.keyword | Hydroxyapatite | - |
dc.contributor.alternativeName | Park, Jong Chul | - |
dc.contributor.alternativeName | Lee, Mi Hee | - |
dc.contributor.affiliatedAuthor | 박종철 | - |
dc.contributor.affiliatedAuthor | 이미희 | - |
dc.citation.volume | 201 | - |
dc.citation.number | 9~11 | - |
dc.citation.startPage | 5729 | - |
dc.citation.endPage | 5732 | - |
dc.identifier.bibliographicCitation | SURFACE & COATINGS TECHNOLOGY, Vol.201(9~11) : 5729-5732, 2007 | - |
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