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Patient quality of recovery on the day of surgery after propofol total intravenous anesthesia for vitrectomy: A randomized controlled trial

 Se Hee Na  ;  Kyu Hee Jeong  ;  Dahae Eum  ;  Jin Ha Park  ;  Min-Soo Kim 
 MEDICINE, Vol.97(40) : e12699, 2018 
Journal Title
Issue Date
Adult ; Aged ; Aged, 80 and over ; Ambulatory Surgical Procedures ; Anesthesia Recovery Period* ; Anesthesia, General/methods* ; Anesthesia, Intravenous ; Anesthetics, Inhalation/administration & dosage* ; Anesthetics, Intravenous/administration & dosage* ; Drug Therapy, Combination ; Female ; Humans ; Isoflurane/administration & dosage ; Isoflurane/analogs & derivatives* ; Male ; Middle Aged ; Piperidines/administration & dosage ; Propofol/administration & dosage* ; Time Factors ; Vitrectomy/methods* ; Young Adult
BACKGROUND: Vitrectomy under general anesthesia is considered as a candidate for ambulatory surgery. An anesthetic method with high quality of postoperative recovery should be selected for successful ambulatory surgery. We thus compared quality of postoperative recovery on the day of vitrectomy using the Quality of Recovery (QoR)-40 questionnaire between propofol total intravenous anesthesia (propofol group) and desflurane inhalation anesthesia (desflurane group) as the 2 representative anesthetic methods. METHODS: Eighty-four patients (20-80 years old) undergoing elective vitrectomy under general anesthesia were randomized into 2 groups. The propofol group received propofol and remifentanil using effect-site target-controlled infusion (TCI), and the desflurane group received desflurane inhalation and remifentanil using effect-site TCI. We assessed quality of recovery at 6 hours after surgery through interviews using the QoR-40 questionnaire. We also collected data related to recovery and complications during emergence and recovery period. RESULTS: The median of QoR-40 score on the day of surgery was significantly higher in the propofol group than that in the desflurane group (181.0 vs 169.5, respectively; P = .033). In particular, propofol group had significantly higher scores for physical comfort and physical independence dimensions. The amount of remifentanil administered was significantly higher, and the emergence time was significantly longer in propofol group. However, there were no significant differences in other complications between the 2 groups. CONCLUSIONS: Propofol total intravenous anesthesia provided significantly better quality of recovery on the day of surgery than desflurane inhalation anesthesia.
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1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Min Soo(김민수) ORCID logo https://orcid.org/0000-0001-8760-4568
Na, Se Hee(라세희) ORCID logo https://orcid.org/0000-0003-4208-0769
Park, Jin Ha(박진하) ORCID logo https://orcid.org/0000-0002-1398-3304
Eum, Dahae(음다혜) ORCID logo https://orcid.org/0000-0003-0048-1476
Jeong, Kyu Hee(정규희)
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