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PDZ-based adaptor proteins in epithelial anion transport and VIP receptor regulation

DC Field Value Language
dc.contributor.author지헌영-
dc.contributor.author박현우-
dc.contributor.author김경환-
dc.contributor.author이민구-
dc.date.accessioned2018-10-15T16:40:38Z-
dc.date.available2018-10-15T16:40:38Z-
dc.date.issued2009-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/163592-
dc.description.abstractPolarized protein deposition at the apical and basolateral membranes of epithelial cells is critical for the asymmetrical transport of ions and fluids across the epithelia. PDZ-based modular adaptor proteins are expressed in the junctional areas in epithelial cells and are generally part of a molecular scaffold that determines the localization and activity of ion channels, receptors, and other signaling molecules to their correct spatial arrangement for proper response to diverse stimuli. Hence, understanding the regulatory mechanisms of channels and receptors via PDZ-based adaptors will provide valuable insights into the physiology of epithelial cells as well as pathophysiology of many human diseases including cystic fibrosis.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfJournal of Medical Investigation-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rightshttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdaptor Proteins, Vesicular Transport/physiology*-
dc.subject.MESHAnimals-
dc.subject.MESHAnions/metabolism-
dc.subject.MESHBiological Transport/physiology-
dc.subject.MESHEpithelial Cells/physiology*-
dc.subject.MESHHumans-
dc.subject.MESHPDZ Domains/physiology*-
dc.subject.MESHReceptors, Vasoactive Intestinal Peptide/metabolism-
dc.subject.MESHTight Junctions/physiology-
dc.titlePDZ-based adaptor proteins in epithelial anion transport and VIP receptor regulation-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine-
dc.contributor.departmentDept. of Pharmacology-
dc.contributor.googleauthorHeon Yung Gee-
dc.contributor.googleauthorHyun Woo Park-
dc.contributor.googleauthorKyung Hwan Kim-
dc.contributor.googleauthorMin Goo Lee-
dc.contributor.localIdA03971-
dc.contributor.localIdA01743-
dc.contributor.localIdA00311-
dc.contributor.localIdA02781-
dc.relation.journalcodeJ03473-
dc.identifier.pmid20224210-
dc.contributor.alternativeNameGee, Heon Yung-
dc.contributor.alternativeNamePark, Hyun Woo-
dc.contributor.alternativeNameKim, Kyung Hwan-
dc.contributor.alternativeNameLee, Min Goo-
dc.contributor.affiliatedAuthorGee, Heon Yung-
dc.contributor.affiliatedAuthorPark, Hyun Woo-
dc.contributor.affiliatedAuthorKim, Kyung Hwan-
dc.contributor.affiliatedAuthorLee, Min Goo-
dc.citation.volume56-
dc.citation.numberSuppl.-
dc.citation.startPage302-
dc.citation.endPage305-
dc.identifier.bibliographicCitationJournal of Medical Investigation, Vol.56(Suppl.) : 302-305, 2009-
dc.identifier.rimsid58825-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pharmacology (약리학교실) > 1. Journal Papers

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