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Characteristics of Acromegaly in Korea with a Literature Review

Authors
 Jae Won Hong  ;  Cheol Ryong Ku  ;  Sun Ho Kim  ;  Eun Jig Lee 
Citation
 Endocrinology and Metabolism (대한내분비학회지), Vol.28 : 164-168, 2013 
Journal Title
 Endocrinology and Metabolism (대한내분비학회지) 
ISSN
 2093-596X 
Issue Date
2013
Keywords
Acromegaly ; Growth hormone ; Pituitary neoplasms
Abstract
Acromegaly is a slowly progressive disease caused by excessive growth hormone (GH), which is related to a GH secreting pituitary tumor in most cases. Herein, we describe the epidemiology, clinical characteristics, and treatment of acromegaly in Korea with a literature review. The average annual incidence of acromegaly in Korea was 3.9 cases per million people, which was within the range of previous Western studies. The primary treatment for acromegaly was also transsphenoidal adenomectomy, which accounted for 90.4% of patients whose primary therapeutic options were known. The overall surgical remission rates were 89%, 87%, 64%, 70%, and 50% for modified Hardy classification I, II, IIIA, IIIB, and IV, respectively. An updated and larger study regarding the treatment outcome of medical/radiotherapy in Korean acromegalic patients is needed.
Files in This Item:
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DOI
10.3803/EnM.2013.28.3.164
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Ku, Cheol Ryong(구철룡) ORCID logo https://orcid.org/0000-0001-8693-9630
Kim, Sun Ho(김선호) ORCID logo https://orcid.org/0000-0003-0970-3848
Lee, Eun Jig(이은직) ORCID logo https://orcid.org/0000-0002-9876-8370
Hong, Jae Won(홍재원)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163342
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