Purpose : This study aimed to investigate the incidence of intravenous extravasation and the risk factors
associated with the use of peripheral intravenous catheters in adults. Method : This prospective observational
study included 203 adult patients admitted to the general ward who received non-chemotherapy vesicant drug
infusion treatments. Data were analyzed using frequencies, percentage, means, standard deviations, and odds
ratios (ORs) from multiple logistic regressions. Results : The incidence of extravasation was 43.3%. Risk
factors for intravenous extravasation included continuous injections (OR=5.35, 95% CI [1.38, 20.83]), and
parenteral nutrition (OR=3.53, 95% CI [1.43, 8.73]). Conclusion : The present findings revealed that
gastrointernal medicine problems, continuous injection, and parenteral nutrition were related to intravenous
extravasation. Further research is necessary to reduce the incidence of extravasation related to peripheral
intravenous catheterization in adults, and to prevent secondary complications. Finally, patients should be provided
appropriate and continuous care based on the type of intravenous infusion.