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Recurrent spontaneous hepatic rupture in pregnancy

Authors
 Gwan Hee Han  ;  Min-A Kim 
Citation
 MEDICINE, Vol.97(29) : e11458, 2018 
Journal Title
 MEDICINE 
ISSN
 0025-7974 
Issue Date
2018
MeSH
Adult ; Conservative Treatment/methods* ; Delivery, Obstetric/methods ; Female ; Gestational Age ; HELLP Syndrome/diagnosis* ; HELLP Syndrome/therapy ; Humans ; Liver/pathology* ; Liver Diseases/etiology* ; Liver Diseases/therapy ; Magnetic Resonance Imaging ; Pregnancy ; Recurrence ; Rupture, Spontaneous/therapy ; Tomography, X-Ray Computed
Abstract
RATIONALE: Spontaneous and repeated hepatic ruptures caused by hemolysis, elevated liver enzymes, and low platelets (HELLP) syndrome are uncommon but life-threatening conditions that rarely occur early in the second trimester of pregnancy. PATIENT CONCERNS: We describe a patient who experienced spontaneous hepatic ruptures in the absence of hypertension during the early second trimesters of both her first and second pregnancies. DIAGNOSES: A 34-year-old multiparous woman without hypertension was admitted at 21 weeks' gestation because of a spontaneous hepatic rupture with hemoperitoneum. Four years previously, the patient had undergone an exploratory laparotomy during her first pregnancy that involved the ligation of bleeders, because a hepatic capsule rupture had caused hemoperitoneum development. INTERVENTIONS: Unlike the first pregnancy, she was managed nonsurgically and conservatively during the second pregnancy, and she underwent frequent laboratory analyses and magnetic resonance imaging follow-up. On day 11 of the patient's hospital admission, we decided to deliver the baby at 23 weeks' gestation, because her condition had deteriorated. OUTCOMES: Non-surgical management improved the patient's outcome, and the baby was born alive, even though the pregnancy was in the early second trimester and the maternal condition was deteriorating rapidly. LESSONS: HELLP syndrome without hypertension and the recurrence of an intrahepatic rupture at an extremely premature gestational age are rare. This patient's findings suggested HELLP syndrome, which was subsequently diagnosed. This patient's clinical course highlights the difficult decisions made by clinicians for mothers and fetuses.
Files in This Item:
T201802300.pdf Download
DOI
10.1097/MD.0000000000011458
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Min A(김민아)
Han, Gwan Hee(한관희) ORCID logo https://orcid.org/0000-0001-5263-4855
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/163148
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